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Why Does Hair Turns to Gray

Explore the molecular structure of melanin, the role of catalase enzyme, and the impact of H2O2 on hair color changes. Learn about the experimental activities that demonstrate the effects of these factors on hair pigmentation. Discover the connection between stress, lifestyle, and nutrition on graying hair.

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Why Does Hair Turns to Gray

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  1. Nature Sunday Academy, 2015-2016 Nanotechnology and Biotechnology-project 2 Why Does Hair Turns to Gray Yuqian Xing, Minh Duong, Xiao Liu, Julia Zhao Department of Chemistry, University of North Dakota Grand Forks, ND 58202

  2. Variety of the Hair Colors How many colors for human hair? • Hair colors are associated with ethnic groups and can be separated into 6 kinds: • Blond, • Blond brown, • Brown, • Brown black, • Black, • Red.

  3. What decide the hair colors? Pigment: melanin Black and brown eumelanin Molecular Structure of eumelanin Various amounts and ratios of two different types of melanin result in the variety of the hair colors

  4. The reason which causes hair color to turn gray when people get older is the alteration of melanin level. Any other reason? New research discovery: H2O2

  5. Knowledge about enzyme? Catalase 2 H2O2 → 2 H2O + O2 The other main reason of achromotrichia (hair turn gray) is the reduction of catalase synthesized when people aging, which causes the accumulation of H2O2 in hair follicle.

  6. Experimental activity 1-Hair in H2O2 Step 1: Prepare three empty clean vials. ② ③ ①

  7. Experimental activity 1-Hair in H2O2 Step 2: Add 20 ml of solution to each vial.① and② are 1M H2O2; ③ is pure water, used as a negative control.

  8. Experimental activity 1-Hair in H2O2 Step 3: Add 100 μl catalase to vial ② gradually and slowly. It is obvious to see the bubbles generated in the solution.

  9. Experimental activity 1-Hair in H2O2 Step 4: Wait for about 10 minutes until little bubbles observed in the vial, then put the hairs in each vials.

  10. Experimental activity 1-Hair in H2O2 Step 5: After 2-3 hours incubation, color fading of hair is observed in vial ① only .

  11. Experimental activity 1-Hair in H2O2 The reaction is slow. If goes to 24 hours, the results will be:

  12. Experimental activity 2- Color bleached by H2O2 Step 1: Prepare three vials with 20 ml of dye solution. 1a 2a 3a

  13. Experimental activity 2- Color bleached by H2O2 Step 2: add 100 ul catalase to vial 2 and 1ml H2O2 to vial 1 and 2. 1a 2a 3a

  14. Factors may contribute to gray hair Stress Life style: nutrition, sleep well… Reduce stress and live in a health life style

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