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RNR polimerazės III promotoriai

RNR polimerazės III promotoriai. Jungiasi TFIIIA. Jungiasi TFIIIC. Jungiasi TFIIIC. Jungiasi TFIIIC. TFIIIA ir TFIIIC padeda prisjungti TFIIIB transkripcijos faktoriui. RNR polimerazės II promotoriai. Šis promotorius dažniausiai naudojamas embrioninio vystymosi metu.

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RNR polimerazės III promotoriai

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  1. RNR polimerazės III promotoriai Jungiasi TFIIIA Jungiasi TFIIIC Jungiasi TFIIIC Jungiasi TFIIIC TFIIIA ir TFIIIC padeda prisjungti TFIIIB transkripcijos faktoriui

  2. RNR polimerazės II promotoriai Šis promotorius dažniausiai naudojamas embrioninio vystymosi metu

  3. Kompleksą gali sudaryti virš 85 polipeptidų

  4. 1. Covalent modification of histones • Amino terminals of histones are modified in various ways • Acetylation; phosphorylation; methylation Adds acetyl groups, thereby loosening the interaction between histones and DNA Removes acetyl groups, thereby restoring a tighter interaction

  5. These effects may significantly alter gene expression • 2. ATP-dependent chromatin remodeling • The energy of ATP is used to alter the structure of nucleosomes and thus make the DNA more accessible Proteins are members of the SWI/SNF family Acronyms refer to the effects on yeast when these enzyme are defective Mutants in SWI are defective in mating type switching Mutants in SNF are sucrose non-fermenters

  6. Skirtingų organizmų SWI/SNF kompleksai

  7. Chromatino surinkimo ir transkripcinės aktyvacijos, dalyvaujant SWI–SNF, modelis

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