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Osman F, Saleh F, Corrigan M, Jackson T, Cil T. University of Toronto, Toronto, Canada

Increased Postoperative Complications in Bilateral Mastectomy Patients Compared to Unilateral M astectomy: An Analysis of NSQIP Database. Osman F, Saleh F, Corrigan M, Jackson T, Cil T. University of Toronto, Toronto, Canada. Introduction.

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Osman F, Saleh F, Corrigan M, Jackson T, Cil T. University of Toronto, Toronto, Canada

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  1. Increased Postoperative Complications in Bilateral Mastectomy Patients Compared to Unilateral Mastectomy: An Analysis of NSQIP Database Osman F, Saleh F, Corrigan M, Jackson T, Cil T. University of Toronto, Toronto, Canada

  2. Introduction • The rate of contralateral prophylactic mastectomy among women with unilateral breast cancer has increased • Incidence of contralateral breast cancer is very low • Post-operative complications: Bilateral > Unilateral?

  3. Method ACS- NSQIP Data 2007-2010 All Mastectomy Patients N= 20,322 High Risk Pre-operative Characteristics Steroids, Infections Dialysis, Etc. N= 1194 Other procedures (Reconstruction, Axillary dissection etc.) N= 12, 769 Two Sentinel Node Biopsy Code N= 1,426 Ambiguous coding and Missing Data N= 714

  4. Results: Baseline Characteristics

  5. Results **P-value <0.05

  6. Multivariable Analysis of Overall Complications

  7. Limitations of the Study • Only Short-term outcomes (30-day) • Cancer stage not reported in NSQIP data • Procedural codes: CPM • No Reconstruction

  8. Conclusion • Bilateral mastectomy appears to be associated with an increased risk of overall post-operative wound and other infections. • Further studies are warranted to examine short term and long-term complications of CPM and whether these complications delay treatment.

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