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SQUAMOUS PAPILLOMA

SQUAMOUS PAPILLOMA. a benign proliferation of stratified squamous epithelium. a papillary or verruciform mass. a soft, painless, usually pedunculated, exophytic nodule with numerous fingerlike surface projections ("cauliflower" or wartlike appearance ).

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SQUAMOUS PAPILLOMA

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  1. SQUAMOUS PAPILLOMA

  2. a benign proliferation of stratified squamous epithelium. a papillary or verruciform mass

  3. a soft, painless, usually pedunculated, exophytic nodule with numerous fingerlike surface projections ("cauliflower" or wartlike appearance )

  4. human papillomavirus (HPV) at least 24 types are associated with lesions of the head and neck totally integration with the DNA of the host cell Viral subtypes6 and 11 have been identified in up to 50% of oral papillomas less than 5% in normal mucosal cells.

  5. themost common of the soft tissue masses arising from the soft palate

  6. Pointed projections blunted projections

  7. A firm, white, rough, exophytic, pedunculated, nontender soft tissue enlargement on the right ventral tongue.

  8. Histopathologic Features a proliferation of keratinized stratified squamous epithelium arrayed in fingerlike projections

  9. fibrovascular connective tissue cores may show inflammatory changes

  10. hyperkeratosis . acanthosis loose connective tissue

  11. Granular layer Keratin layer

  12. Occasional ………basilar hyperplasia and mitotic activity a normal maturation pattern

  13. Koilocytes virus-altered epithelial clear cells with small dark (pyknotic) nuclei in the prickle cell layer keratohyaline granules cleared cytoplasm, shrunken, irregular nuclei

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