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”بسم الله الرحمن الرحيم“ Pseudomonas. Prof. Khalifa Sifaw Ghenghesh. Pseudomonas aeruginosa. Oxidase-positive, Strict aerobe, Gram –ve rods A major Cause of Nosocomial Infections. Infection Occur in Patients with Altered Host Defences, Wounds or Burns. In Non-Hospitalized Patients:
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”بسم الله الرحمن الرحيم“Pseudomonas Prof. Khalifa Sifaw Ghenghesh
Pseudomonas aeruginosa • Oxidase-positive, Strict aerobe, Gram –ve rods • A major Cause of Nosocomial Infections. • Infection Occur in Patients with Altered Host Defences, Wounds or Burns. • In Non-Hospitalized Patients: • Vehicles of Transmission:
LABORATORY DIAGNOSIS: • On BA • Irregular, b-hemolytic colonies • Oxidase-positive • O-F test >> Aerobic • On NA • Bluish, irregular colonies • TREATMENT • Resistant to antimicrobial agents • CONTROL
Resistance of Pseudomonas aeruginosa isolated from different clinical sources to antibiotics Antibiotic No. (%) resistant (n=235) ------------------------------------------------------ Cefsulodin 61 (26) Gentamicin 102 (43) Carbenicillin 113 (48)
Resistance of Pseudomonas spp isolated from hospital and community cockroaches to antibiotics No. (%) resistant Antibiotic Hospital Community Total (n=34) (n=9) (n=43) --------------------------------------------------------------------------------- Ampicillin 33 (97) 9 (100) 42 (97) Amoxicillin- 33 (97) 9 (100) 43 (100) clavulanic acid Ceftazidime 0 (0.0) 0 (0.0) 0 (0.0) Cephalothin 34 (100) 9 (100) 43 (100) Chloramphenicol 33 (97) 9 (100) 42 (97) Gentamicin 4 (12) 0 (0.0) 4 (9.5) Nalidixic acid 34 (100) 9 (100) 43 (100) Nitrofurantoin 34 (100) 9 (100) 43 (100) Ciprofloxacin 0 (0.0) 0 (0.0) 0 (0.0) Tetracycline 32 (94) 9 (100) 41 (95.3) Trimethoprim- 34 (100) 9 (100 43 (100) sulphamethoxazole