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Distal Aortic Fenestration Facilitates Endovascular Elephant Trunk Completion And Eliminates Retrograde False Lumen Filling Of Chronic Dissection. Eric E. Roselli, MD, Akshat C. Pujara, BA. Chronic Dissection Repair. Controversy: Open vs Endovascular Open - Morbid - Need for reoperation
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Distal Aortic Fenestration Facilitates Endovascular Elephant Trunk Completion And Eliminates Retrograde False Lumen Filling Of Chronic Dissection Eric E. Roselli, MD, Akshat C. Pujara, BA
Chronic Dissection Repair Controversy: Open vs Endovascular Open - Morbid - Need for reoperation not always eliminated Endovascular - Anatomic limitations - Thromboexclusion of FL unpredictable – retrograde filling
Novel Treatment Strategy Objective: Construct distal landing zone during 1st stage elephant trunk repair to facilitate endovascular completion
Patients July 2007 to August 2009 n = 15 Age 57 + 10 years Max aortic diameter 6.0 + 1.0 cm 1st Stage Elective n = 5 Urgent n = 10
Operative Technique Initial Presentation Time from Initial Event to 1st Stage Elephant Trunk 17 months (range 3-33) 7 Type A 8 Type B Proximal Landing Zone
Open Fenestration Heart retracted and aorta exposed through posterior pericardium Dissection Flap Fenestrated
Modified Distal Landing Zone Pre-Op Post-Op Fenestrated Segment Dissection Flap DHCA 19 ± 6 min ACP 55 ± 10 min
Endovascular Completion Emergent Urgent n = 2 n = 3 2nd Stage n = 10 Elective Median interval ET to completion: 60 days (IQR 4 - 114)
Endovascular Completion Antegrade 4, Retrograde 11 Circumferential Seal Clips Marking Seal Zone Commercially available devices
Early Outcomes Technical success in all patients One hospital death - Left leg weakness, BMI 46 kg/m2 - Pulmonary embolism POD 19 No strokes No renal failure No respiratory failure
Intermediate Outcomes Median follow-up 11 months (IQR 6 - 17) • 93% overall survival • Mean decrease aortic diameter 0.5 cm • No retrograde false lumen filling • 7 endoleaks (1 type I, 6 type II) • 2 endovascular reinterventions
Distal Aortic Fenestration Safe technique for constructing distal landing zone Good intermediate-term outcomes Eliminates retrograde false lumen filling Promotes aortic remodeling