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Explore the innovative use of acoustic tweezers in manipulating cells for research and medical applications. Acoustic patterning of particles and cells, separation of cancer cells from blood cells, and single particle manipulation are discussed in this cutting-edge technology.
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Acoustic Tweezers: Manipulating Cells using Sound Tony Jun Huang, Ph.D. Professor of Engineering Science and Mechanics The Pennsylvania State University junhuang@psu.eduhttp://www.esm.psu.edu/huang/
Inlet Outlet IDTs Inlet Outlet IDTs Acoustic Patterning of Particles/Cells J. Shi, D. Ahmed, X. Mao, S.-C. S. Lin, and T. J. Huang, Lab on a Chip, 2009, 9, 2890-32895. X. Ding, J. Shi, S.-C. S. Lin, S. Yazdi, B. Kiraly, and T. J. Huang, Lab on a Chip, Vol. 12, pp. 2491-2497, 2012.
Acoustic Separation of Cancer Cells from Blood Cells SAW on (movie) Cancer cells Cancer cells + Blood cells Blood cells Cancer cells SAW on (stacked image) Cancer cells + Blood cells Blood cells Ding, et al,, Proceedings of the National Academy of Sciences of the United States of America (PNAS), Vol. 111, pp. 12992-12997, 2014
Single Particle Manipulation Using Acoustic Tweezers 100 µm X. Ding, S. Lin, B. Kiraly, H. Yue, S. Li, J. Shi, S. J. Benkovic, and T. J. Huang, Proceedings of the National Academy of Sciences of the United States of America (PNAS),Vol. 109, pp.11105-11109 (2012).