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Standards of Medical Care in Diabetes - 2008. Jeri Jennings Mills, RD/LD, CDE Sami Wood, RD/LD, CDE OSUMC Diabetes Education. Types of Diabetes. Type 1 diabetes IDDM juvenile onset type I Type 2 diabetes NIDDM adult onset type II. Gestational diabetes (GDM) Others
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Standards of Medical Care in Diabetes - 2008 Jeri Jennings Mills, RD/LD, CDE Sami Wood, RD/LD, CDE OSUMC Diabetes Education
Types of Diabetes • Type 1 diabetes • IDDM • juvenile onset • type I • Type 2 diabetes • NIDDM • adult onset • type II
Gestational diabetes (GDM) • Others • Genetic defects in beta cell function • Genetic defects in insulin action • Diseases of the pancreas (cystic fibrosis) • Drug induced (AIDS Tx/organ transplantation) • MODY
Some patients cannot be clearly classified as type 1 or type 2 • LADA • Type 1.5
How to diagnosis diabetes • FPG is the preferred diagnostic test • Use of the A1c for diagnosis is not recommended at this time
Three diagnostic criteria: • FPG > 125 mg/dL*, or • “Casual” plasma glucose > 200 mg/dL & sx’s of high blood sugar, or • 2-h plasma glucose* > 200 mg/dl (during an 75 gram glucose OGTT) *needs repeat confirmation on different day
Screening for diabetes In diabetes, the same tests used to screen for diabetes, also diagnose diabetes “There is no more ‘screening’ for type 2”!
Screening for type 1 diabetes • Screening asymptomatic individuals for auto-antibodies is not currently recommended • Clinical studies are being done to test various methods of preventing type 1
Joe is 30 years old with a BMI of 29. He does not exercise. His father has “borderline” diabetes. Joe has no symptoms of diabetes. Should he be tested? (B) • Yes • No
Testing for type 2 • About 1/3 of all people with diabetes may be undiagnosed • Average dx is 7-10 years after onset • Type 2 DM is frequently diagnosed after complications appear • So…who should be tested?
All adults with BMI >24 and a risk factor below… • Physical inactivity • 1st degree relative with DM • High-risk ethnic group • Women w/hx GDM and/or PCOS • HTN • HDL <35 or trig >250 • IGT or IFG on previous testing • Acanthosis nigricans • Hx of CVD • Age 45 if none of the above apply & q 3 yrs…
“Type 2 diabetes has a long asymptomatic phase and significant clinical risk markers. Diabetes may be identified anywhere along a spectrum of clinical scenarios”.
Prediabetes is NOT “borderline diabetes”! • Fasting: 100-125 – Impaired fasting glucose (IFG) • 2-hr glucose: 140-199 – Impaired glucose tolerance (IGT) Both IFG and IGT are considered risk factors for future diabetes & CVD and should be treated.
Testing for type 2 diabetes in asymptomatic children(Table 4 page S14) BMI >85th percentile for age & sex, weight for height or weight >120% of ideal for height plus 2 of the following risk factors…
Family hx in 1st or 2nd degree relative • Race/ethnicity (African American, Native American, Latino, Asian, Pacific Islander) • Signs of insulin resistance (Acanthosis nigricans, hypertension, dyslipidemia, or PCOS) • Maternal history of diabetes or GDM
When to test for type 2 diabetes in children (Table 4 page S14) • Age of initiation: 10 yrs or at onset of puberty • Frequency: every 2 yrs • Test: FPG preferred
Gestational Diabetes(Table 5 Page S15) If high risk factors present, screen for diabetes ASAP after pregnancy confirmed. • Marked obesity • Hx of GDM • Previous large-for-gestation-age infant • Glycosuria • PCOS or “insulin resistant” • Fam Hx DM
Low risk factors for GDM • Age <25 yrs • Weight normal before pregnancy • Member of ethnic group with low prevalence of diabetes • No known diabetes in first degree relative • No history of abnormal OGTT or GDM • No history of poor obstetric outcome
Prevention/delay of type 2 diabetes after GDM • Lifestyle modification counseling important • Monitor for DM every 1-2 yrs • Treat other CVD risk factors (tobacco use, HTN, dyslipidemia) • Consider metformin in addition to lifestyle counseling
Reducing Diabetes Risk Lifestyle modification was shown to have the greatest effect in two well-controlled studies: • Diabetes Prevention Program (DPP): reduced risk of developing diabetes by 58% • Finnish Diabetes Prevention Study showed direct relationship between lifestyle intervention and decrease in diabetes
Self monitoring of blood glucose • 2-4x/day if on insulin • If on oral agents or MNT, SMBG is done to achieve glycemic control • May include postprandial checks • Routinely evaluate technique and patient’s ability to use data to adjust food intake, exercise, & medications.
An A1C should be tested at least once yearly. (E) • True • False
The A1C A “3 month average” • should be checked at initial assessment - then regularly… • 2x/year in patients meeting tx goals, • quarterly in patients who are not meeting tx goals
The ADA A1C goal for nonpregnant adults with diabetes is <7%. (A) • True • False
ADA Glycemic Goals(Table 8, S18) • A1c <7% (~ plasma glucose of 170 mg/dL) • Pre-meal: 90-130 mg/dl • Post-meal <180 (1-2 hrs post meal)
Glycemic control is fundamental to the management of diabetes • UKPDS demonstrated significant reductions in microvascular and neuropathic complications with intensive therapy in type 2 • DCCT demonstrated similar findings in type 1 diabetes
Medical Nutrition Therapy (MNT) Individuals who have pre-diabetes or diabetes should receive individualized MNT to achieve treatment goals, preferably by a registered dietitian & certified diabetes educator (RD/CDE)
The ADA diabetic diet is the current recommendation for Medical NutritionTherapy (MNT). (A,E) • True • False
Hospital diets continue to be ordered by calorie levels based on the “ADA diet”. Since 1994, the ADA has not endorsed any single meal plan. The term “ADA diet” should no longer be used. I think that means it’s extinct!!
Physical Activity – Precautions • EKG monitoring - should be considered before starting aerobic activity in the sedentary patient • Autonomic Neuropathy – can decrease cardiac responsiveness in exercise. Is strongly associated with CVD in people with diabetes
Physical Activity(precautions) • Dilated Eye Exam:resistance training is contraindicated if retinopathy is present (can trigger vitreous hemorrhage or retinal detachment) • Foot Exam: Decreased pain sensation results in risk of skin breakdown, infection and of Charcot joint destruction. Consider non-weight bearing like swimming, bicycling, or arm exercises
Physical Activity(precautions) • Hyperglycemia – in type 1 DM: Avoid exercise in presence of ketosis. Muscles can’t use sugar if not enough insulin available • Hypoglycemia – Exercise increases insulin sensitivity. Low BS can result if pt on insulin or sulfonylurea drugs • Check BS prior to exercise, during and after
Assessment of depression should be included in the medical management of diabetes. (E) • True • False
Psychosocial Assessment • Depression is greater in individuals with diabetes • Can impact self-care behaviors • Screen for depression It is important to establish that emotional well-being is part of diabetes management.
Patients with type 2 DM should have a dilated eye exam within 5 years of diagnosis. (B) • True • False
Type 1 DM: dilated, comprehensive eye exam within 3-5 yrs of diagnosis, then yearly • Type 2 DM: dilated, comprehensive eye exam shortly after diagnosis & then yearly • Pregnant with pre-existing diabetes: eye exam in 1st trimester; f/u during pregnancy & for 1 year after
Individuals with diabetes should be started on statin therapy if they do not have CVD but are over age 40. (A) • True • False
Recommendations for those without CVD and under age 40 • Trigs <150 • HDL >40 in men • HDL >50 in women • LDL <100 • (consider statin therapy if LDL >100) • LDL <70 in those with overt CVD
BP Goal <130 systolic/< 80 diastolic • Consider daily aspirin (75-162 mg/day) • In people with diabetes between 30-40 years of age in presence of CV risk factors • Not recommended in anyone <21 yrs of age due to risk of Reye’s Syndrome
Smoking cessation counseling should be a treatment component of diabetes care. (B) • True • False
SMOKING • Should be #1intervention • We have a smoking cessation counselor at OSUMC!!
In patients with type 2 DM, ACE’s and ARB’s have been shown to protect kidney function. (A) • True • False
Complications: Kidney • ACE’s &/or ARB’s have been shown to delay nephropathy (contraindicated in pg) • Screen annually for microalbuminuria: • in type 1 DM, diagnosed > 5 yrs, • in type 2 DM at diagnosis, and • during pregnancy • Screen annually for serum creatinine & GFR
Complications: Kidneys • Dietary protein reduction may be needed if CKD present • Diabetic nephropathy is the single leading cause of ESRD (See Table 12 & 13 pg S30 for specific information)