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What is LINC?

What is LINC?. A multicenter, randomized , controlled trial designed to evaluate the efficacy and safety of: LUCAS concept for resuscitation of OHCA including defibrillation during ongoing compressions vs. manual CPR according to 2005 guidelines. Objectives. Primary

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What is LINC?

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  1. What is LINC? • A multicenter, randomized, controlled trial • designedtoevaluate the efficacy and safety of: • LUCAS concept for resuscitation of OHCA includingdefibrillationduringongoingcompressionsvs. • manual CPR accordingto 2005 guidelines

  2. Objectives Primary Superiority in 4-hr survival Secondary Survival upto 6 month with good neurological outcome CPC 1-2

  3. Inclusion/Exclusion criteria Inclusion criteria Unexpected adult out-of-hospital cardiac arrest where an attempt of resuscitation is considered appropriate Exclusion critera Traumatic cardiac arrest, including hanging Age believed to be < 18 years Known pregnancy Patients body size not fitting the LUCAS Defibrillated -before LUCAS arrives at scene -crew witnessed VF/VT with ROSC some of the most viable patients have been excluded

  4. Outcome 4-hour survival: Risk difference -0.05% 95% C.I. -3.32 – 3.23, p=1.00 4-hour survival 23.6% 23.7%

  5. Conclusions Mechanicalchestcompressionsusing the LUCAS device in combination withdefibrillationduringongoingcompressionsprovided no improved 4-hour survivalcomparedtoconventional manual chestcompressions in out-of-hospital CA patients Therewasgoodneurologicoutcome in the vastmajorityof the survivors in bothgroups Thus, in clinicalpractise CPR with the LUCAS device and defebrillationduringongoingcompressionsseemstohavesimilareffectiveness as manual chestcompressions

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