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(a). (b). (c). -. +. -. TNF PMA. -. -. +. 75. IP: ā I B IB : āp65 COOH. p65 /RelA. -. +. -. -. +. -. NH 2 p65. LMB PMA. -. -. +. -. -. +. 50. 75. 75. p65 /RelA. IB : āp65 COOH ā I B. Nucleus. Cleaved p65. 50. 50. I B. 37. 37.
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(a) (b) (c) - + - TNF PMA - - + 75 IP: āIB IB: āp65 COOH p65/RelA - + - - + - NH2p65 LMB PMA - - + - - + 50 75 75 p65/RelA IB: āp65 COOH āIB Nucleus Cleaved p65 50 50 IB 37 37 Nucleus Cytosol - + - - + - LMB PMA - - + - - + 75 75 p65/RelA Cleaved p65 50 50 IB 37 37 Nucleus IP: āIB IB: āp65 COOH IP: āIB IB: āp65 NH2