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Treatment with Enoxaparin and Tirofiban in acute MI (TETAMI) M.Cohen et al, Beth Israel Hospital, NJ. 1224 STEMI pts, no reperfusion, < 24 hours from onset 4 treatment groups Enox 30 mg iv plus 1 mg/Kg sc bd alone Enox 30 mg iv plus 1 mg/Kg sc bd with Aggrastat 100 ug/Kg IV
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Treatment with Enoxaparin and Tirofiban in acute MI (TETAMI) M.Cohen et al, Beth Israel Hospital, NJ • 1224 STEMI pts, no reperfusion, < 24 hours from onset • 4 treatment groups • Enox 30 mg iv plus 1 mg/Kg sc bd alone • Enox 30 mg iv plus 1 mg/Kg sc bd with Aggrastat 100 ug/Kg IV • UFH 70 U/Kg plus 15 U/Kg per hour infusion • UFH 70 U/Kg plus 15 U/Kg inf. with Aggrastat 100 ug/Kg IV • Subgroup analysis showed protective Tirofiban trend in: • Pts treated within 12 hours • LV dysfunction • Study underpowerd for mortality
Outcomes in TETAMI Cohen M. American Heart Association Scientific Sessions 2002.