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MND occurs when specialized nerve cells in the brain and spinal cord, called motor neurons, stop working properly.<br>
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Understanding Motor neuron disease (MND) • Also known as Amyotrophic Lateral Sclerosis (ALS), it is a rare neurodegenerative disease. • MND occurs when specialized nerve cells in the brain and spinal cord, called motor neurons, stop working properly. • Motor Neuron diseases are a rare but severe form of neurodegenerative disease. • It cause the motor nerves in the spine and brain to lose function over a span of time • The two main types of motor neurons are upper motor neurons (UMN) and lower motor neurons (LMN)
Motor Neuron Disease Symptoms The symptoms are divided into three stages – early, middle and advanced. Signs and symptoms in the early stage: • Weakened grip, making it difficult to hold and pick up objects • Muscle pain, cramps, and twitching • Weakness in arms and legs, leading to clumsiness and stumbling • Fatigue • Slurred speech and difficulty swallowing • Breathing trouble • Weight loss due to loss of muscle mass • Inappropriate emotional responses
Signs and symptoms in the middle stage: • Shrinking of muscles • Joint pain • Difficulty in movement • Drooling and problems with swallowing • Difficulty breathing • Changes in personality and emotional states • Memory and language problems
Signs and symptoms in the advanced stage: • Little or no movement • Trouble talking and swallowing • Severe breathing problems • May develop dementia • Some people may also experience insomnia, anxiety, and depression
MND Diagnosis A neurologist examines the person thoroughly by running a series of tests before determining MND, some of which are: • Blood and urine tests • MRI scan • EMG (electromyography) and NCS (nerve conduction study) • Muscle biopsy • Lumbar puncture or spinal tap
MND Treatment • The condition of the prognosis varies, depending on the patient’s type of MND and the age of symptom onset • Supportive and symptomatic treatment can surely help • One can take assistance from multidisciplinary clinics consisting of specialists from varied departments such as: • physical therapy • speech therapy • occupational therapy • respiratory therapy • neurology
Stem cell therapy for MND • Stem Cell Therapy is a potent approach for treating MND and its vitalizing effects, both paracrine and somatic • This treatment helps to improve the repairing mechanism of diseased, dysfunctional, or injured tissue with the help of stem cells • It is proven to mitigate symptoms, slow the progression of the disease, improve the quality of life and increase survival • The beneficial effects of this therapy do not just affect the cells, but are also beneficial to trophic interventions • It mitigates the symptoms of traumatic injuries, autoimmune, inflammatory, neurological, and orthopedic diseases • It helps to reduce inflammation and delay progression