190 likes | 342 Views
Nieuwjaarsreceptie. Faculteit Bètawetenschappen 7 januari 2014. VERBINDEN. Johan Garssen Pharmacology (UIPS), Beta Faculty, UU Immunology, Nutricia-research (Utrecht/ Singapore), DANONE. Verbinden (oud en nieuw) Verbinden van mensen Verbinden van culturen
E N D
Nieuwjaarsreceptie Faculteit Bètawetenschappen 7 januari 2014
VERBINDEN Johan Garssen Pharmacology (UIPS), Beta Faculty, UU Immunology, Nutricia-research (Utrecht/ Singapore), DANONE
Verbinden (oud en nieuw) Verbinden van mensen Verbinden van culturen Verbinden van onderzoekers, expertises Verbinden van food en pharma Verbinden van public en private
Bridging (life sciences) between different cultures/continents
Bridging life sciences between profit and non-profit organisations [valorisation]
UIPS:Translational medicine Drugs/Specialised nutrition Therapy and Prevention Disease Mission: From bench/molecule to bedside
In vivo Human (multi center trial) Translationalpharmacology In vivo Human (proof of concept) In vivo Animal In vitro Human Cells In vitro Animal Cells Use-inspired fundamental research In vitro Mechanistic
Embedding in Life Sciences Utrecht(present collaborations) Hubrecht, developm. biol. Stem cells. WKZ immunology Nutricia/DANONE -research U Med.Center microbiol. oncology metabol. & endocrin. pathol. Allergy Lung UIPS Beta faculty Stratenum CNS Cell Biol. HU Life sciences Proteomics IRAS Pharmacology Arthritis team BIOCEROS Vet. Sci. infect. diseas. & immunol RIVM HU health
MRI analysis Respiratory microbiota Imaging Science InstituteProf Viergever Immunology Infectious DiseasesProf Sanders Animal studies Biomarkers UIPS Prof Garssen Dr Kraneveld NutriBrain studyNeonatology Dr Benders Prof Van Bel Gut development faecalmicrobiota WUR Wageningen Prof Knol Dr Belzer Placenta Biomarkers Immune Biomarkers PathologyDr Nikkels Translational Immunology Prof Prakken 1
"Let medicine be thy food,and food be thy medicine.“ Hippocrates of Cos, Greece460-377 B.C.
Nutrition Pharma • Education: Junior college, Bachelor,Master,PhDs, • Eureka • Awareness (….single vs. multitarget approach) • Translational research valorisation
Bio-active components in pharma versus food Small effects on multiple targets Pharma Food Focussed large effect on single target
From single towards multitarget approaches (cancer) Cachexia Malnutrition Fatigue Systemic inflammation Infections Mucositis … MEDICAL NUTRITION
UTRECHT/SINGAPORE COMPANIES Translational Medicine from bench to bedside
2014 • PUBLIC PRIVATE: speeding up innovation • Asia vs Europe/VS: differences in biomarkers • health/disease, success of intervention • 3. Gap between food and pharma is narrowing • (single vs multitarget approach) • 4. Connect research with education