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BioPhotonics & Physics and Oriental Medicine

BioPhotonics & Physics and Oriental Medicine. Han C. Ryoo, Ph.D. Richard Beard. Ph.D. School of Biomedical Engineering, Science and Health Systems Drexel University, PA 19104 (Details can not be provided for IP protection). Objectives. Improve Healing Process in Diabetic Patients

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BioPhotonics & Physics and Oriental Medicine

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  1. BioPhotonics & Physics and Oriental Medicine Han C. Ryoo, Ph.D. Richard Beard. Ph.D. School of Biomedical Engineering, Science and Health Systems Drexel University, PA 19104 (Details can not be provided for IP protection)

  2. Objectives • Improve Healing Process in Diabetic Patients • Improve Sensitivity of Surface Electrodes • Developing Non-invasive Acupuncture Therapy

  3. Background • Polymorphonuclear leukocytes, PMNs and mononuclear leukocytes, MNLs, have had their migration investigated in vitro over that last 2 decades or more. The influence of magnetic fields, the effect of photons from light emitting diodes (LEDs) at different wavelengths and intensities have been studied, and the use of electromagnetic stimulation at different dielectric relaxation frequencies have been applied in vitro. • The comparison of the relative value of the distance to cell migration under stimulation and without stimulation is recorded as cytokinetics index, K.I., which is a measure of the cytokinesis which is the progress of cell movement in which the migration is enhanced by substances in the cell environment irrespective of a concentration gradient. Cytotaxis is the directional movement of the cells along a chemical gradient formed by chemoattractant while cytokinesis is the process of cell movement in which the migration is enhanced by substances in the cell environment irrespective of a concentration gradient (random migration).

  4. Background (Cont..) • PMNs comprise 58% and MNLs approximately 38 % of normal blood count. MNLs comprise about 10 % monocytes and 90 % of lympocytes while PMN peak emigration occurs within the first 6 hours after an assault on the body. MNLs predominate after 12 hours. Applications of this enhanced migration will be investigated relative to wound healing in diabetic patients, enhanced electrode sensitivity and surface acupuncture therapy.

  5. Approaches • Biomedical Optics & Physics • LEDS with different wavelengths • Magnets (Permanent, Helmholtz Coil) with different Gauss Levels • Optical and Magnetic Interaction of Biological Tissues • Measure Skin Impedance using Invasive (Acupuncture Needles) and Non-invasive (Surface) Electrodes • Input Current < 5mA, Frequency Ranges (500 hz– 10 Mhz)

  6. Equipments & Devices • Impedance Analyzer • Power Supply • Gauss Meter • Helmholtz Coils (Cored, Coreless) • Permanent Magnets • Acupuncture Needles • LEDs (Red, Green, Yellow, Orange) Alcohol, wires, batteries and others.

  7. New Electrode Design for Improved Sensitivity and Healing process New Surface Electrode Design LED Patches for diabetic wound

  8. Magnetic & Optical Interaction on Phantom Tissue

  9. In-Vivo Measurement of Skin Impedance Weak Gauss (<12 G) Strong Gauss (>12 G), Dr. Beard was protected by Metallic Shield. (Implanted Defibrillator < 9G )

  10. Impedance Change by Acupuncture Needle Frequency Ranges: 500 Hz ~ 10 MHz Oscillator Voltage: 5 mV

  11. Electrocardiogram (ECG) by IQ Impedance System with 100 kHz and 5mA The peak-to-peak of ECG signal was improved about 10 % on the average (Lead II Configuration)

  12. In Progress ….

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