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Prediabetes

Prediabetes. Burden. Epidemiology: Health Performance Gaps . Prevalence Risk factors Metabolic syndrome Obesity Clinical risks of p rediabetes Progression to diabetes Complications (eg, retinopathy). Progression to Type 2 Diabetes. Or both. Prediabetes.

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Prediabetes

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  1. Prediabetes Burden

  2. Epidemiology: Health Performance Gaps • Prevalence • Risk factors • Metabolic syndrome • Obesity • Clinical risks of prediabetes • Progression to diabetes • Complications (eg, retinopathy)

  3. Progression to Type 2 Diabetes Or both Prediabetes

  4. Prevalence of Diabetes and Prediabetes in the United States Increased incidence of prediabetes from 2007 to 2010 Diabetes 8.3% of US population Persons (millions) 39% increase Prediabetes 35% of US population CDC and Prevention. National diabetes fact sheet, 2007. http://www.cdc.gov/Diabetes/pubs/pdf/ndfs_2007.pdf. CDC and Prevention. National diabetes fact sheet, 2011. http://www.cdc.gov/diabetes/pubs/pdf/ndfs_2011.pdf.

  5. Prevalence of IFG and IGT in US Adults Without T2DM: NHANES Data Incidence of prediabetes, IFG, and IGT in a representative sample of the US population IFG, impaired fasting glucose; IGT, impaired glucose tolerance; NHANES, National Health and Nutrition Examination Survey ; T2DM , type 2 diabetes mellitus. KarveA, Hayward RA. Diabetes Care. 2010;33:2355-2359.

  6. How Much Does the Metabolic Syndrome Raise the Risk of T2DM? 25.0 T2DM risk, stratified by IFG and metabolic syndrome 21.0(13.1-33.8) 20.0 10.0 Odds Ratio (Confidence Interval) 7.07(3.32-15.1) 5.03 (3.39-7.48) 5.0 1.0 (ref) 1.0 No MetSyn No IFG MetSyn without IFG MetSyn + IFG IFG without MetSyn IFG, impaired fasting glucose; MetSyn, metabolic syndrome; T2DM, type 2 diabetes mellitus. Lorenzo C, et al. Diabetes Care. 2007;30:8-13.

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