Gene expression levels in African Americans vary with both cis and trans genetic ancestry

Nov 27, 2012

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Gene expression levels in African Americans vary with both cis and trans genetic ancestry

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Gene Expression: Protein Synthesis and Genetic Mutation

Why make proteins?. Proteins are made of 20 kinds of amino acids linked together in a specific order. (2 or more polypeptides).All organisms contain and make proteins. Major structural components of your cells, and your body as a whole. i.e., keratin- hair, fingernails, hemoglobin- rbc's, insulin

1.3k views • 27 slides

Gene Expression

Gene Expression. Gene expression?. Biological processes, such as transcription, and in case of proteins, also translation, that yield a gene product. A gene is expressed when its biological product is present and active. Gene expression is regulated at multiple levels.

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African-Americans

African-Americans. 14 th Amendment (1868). Section 1.

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African Americans

African Americans. By:Skyler,Chris,Alexis,Jessie. Main idea.

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Review of the Genetic Material Gene Expression

Review of the Genetic Material Gene Expression. Dr Maha Al- Sulaimani Department of Biochemistry. The Genetic Material/Definition . What is the genetic material?

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Gene Expression

Gene Expression. The human genome contains about 20,325 protein-encoding genes - However, this represents only a small part of the genome Much of the human genome controls protein synthesis - Including the time, speed, and location. Proteins have diverse functions in the body.

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Gene Structure and Gene Expression

Gene Structure and Gene Expression. Each chromosome contains one DNA molecule, which consists of roughly 80 million bases. How these extremely long molecules fit in a nucleus?. They are tightly associated with proteins to form nucleoprotein complex.

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Gene Expression

Gene Expression. Gene: contains the recipe for a protein. 1. is a specific region of DNA on a chromosome. 2. codes for a specific mRNA. mRNA: exits the nucleus and associates with ribosomes. 1. carries the code for a specific protein to the cytoplasm.

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Gene Expression

Gene Expression. 1: Activation (overview), Transcription, Translation.  The Goodwin Equations. Review. An active gene is one that is being transcribed , and whose transcription product is being translated , and whose translation product affects cellular behavior/development.

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Gene expression is controlled at many levels in prokaryotes

Internalization or exclusion of inducers Regulation of transcription initiation Regulation of transcription elongation and termination Regulation of mRNA stability or processing of primary transcripts Regulatlion of translation Regulation of protein activity and stability

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African Americans

African Americans. Beginnings of slavery. 1441 was the start of the European slave trade in Africa. Portuguese captains Antao Concalves and Nuno Tristao capture 12 Africans in Mauritania and take them to Portugal.

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Accurate Estimation of Gene Expression Levels from Digital Gene Expression Sequencing Data

Accurate Estimation of Gene Expression Levels from Digital Gene Expression Sequencing Data. Marius Nicolae and Ion M ă ndoiu (University of Connecticut, USA). Outline. DGE/SAGE- Seq protocol EM algorithm Experimental results Conclusions. RNA- Seq Protocol.

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African Americans

African Americans. Kim Searles, Sam Smith, and Nichole Humbrecht. The Journey. When the first blacks were brought to America it was unclear as to whether they were slaves or indentured servants. Switch White to Black 1600-1700.

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with Gene Expression Programming

Statistical Learning for Event Selection. with Gene Expression Programming. Outline. Introduction to evolutionary computation Gene Expression Programming (GEP) Application of GEP for Event Selection Conclusion. Evolutionary Computation.

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Gene Expression

Gene Expression. Review covering RNA Processing & Translation. Posttranscriptional ( RNA Processing). - Transcription has created a primary transcript (pre mRNA) that is not ready to be exported from the nucleus to the ribosome in the cytosol.

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Normalized gene expression levels

Normalized gene expression levels. shoot. Supplemental Figure 5. Expression patterns of Glyma03g31980 ( CND ) and Glyma17g07330 in 10 soybean tissues.

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GENE EXPRESSION

GENE EXPRESSION. First genes must become AVAILABLE for expression. There are ROAD BLOCKS to becoming available. Exs . Does the cell have the needed DNA sequence?

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Chapters 18 - Regulation of gene expression in eukaryotes : Levels of control of gene expression

Chapters 18 - Regulation of gene expression in eukaryotes : Levels of control of gene expression Short term control (to meet the daily needs of the organism) Long term control (gene regulation in development/differentiation). Differences between prokaryotes and eukaryotes :

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Gene expression

Gene expression. Transcription and Translation. 1. Important Features. a. DNA contains genetic template for proteins. b. DNA is found in the nucleus c. Protein synthesis occurs in the cytoplasm - ribosome.

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Gene Expression

Gene Expression. Early evidence indicating most genes specify the structure of proteins Garrod’s work on inborn errors of metabolism in early 1900s Beadle and Tatum’s work with Neurospora mutants in the 1940s. An “inborn error of metabolism”. Mutations affecting biochemical pathways.

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African Americans

African Americans. Is there an American Dream?. Context. Until the mid 1960’s, still well within living memory, it was still legal to discriminate against African Americans in education, housing and jobs.

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