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Detailed analysis of a young female patient with persistent retrosternal discomfort, including presenting complaints, history, examination, differential diagnosis, and investigative findings. Consultation and treatment recommendations provided.
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A young female patient with persistent retrosternal discomfort. 18th April, 2018 CPC by Surgical Unit – I, Benazir Bhutto Hospital, Rawalpindi
History: • Pain in upper abdomen: • Epigastric pain • Gradual in onset • Initially, mild; severity grew overtime • Intermittent in nature • Non radiating • Dull aching
Pain epigastrium: • Aggravated by food intake particularly after large meals • Pain developed on eating food that lead to restriction of diet for fear of pain • Vomiting associated with pain • Both symptoms were relieved temporarily by medications from local General Practitioners
Heartburn: • Dyspepsia occurred after food intake • Epigastricfullness after meals, relieved after regurgitation • Restriction of food intake secondary to heartburn and pain
Regurgitation: • Regurgitation of sour fluid • Occurring after half an hour to one hour after food intake • Especially on lying down • Containing undigested food particles • Persistent sore - throat
Associated History: • Easy fatigability • Depression and anxiety • Insomnia due to regurgitation • Undocumented Weight Loss with good appetite No history of: • Recurrent cough • Aspiration pneumonia • Dysphagia • Odynophagia • Jaundice • Hematemesis • Altered Bowel Habit • Melena
Past Medical and Surgical History: Psychiatry consultation, BBH – Psychogenic Vomiting ? ? ?
Family History Hypertension Diabetes Hepatitis C - Mother No such history in siblings
EXAMINATION • A young, emaciated female patient, lying comfortably on the bed, well oriented in time, place and person.
General Examination: • HR = 87bpm RR = 17/min • BP = 120/75mmHg Temp = 98 F No: • Pallor + • Jaundice • Cyanosis • Clubbing • Goiter • Raised JVP • Palpable Lymph Nodes
Body Mass Index: Age = 18 years Gender = Female Height = 5 feet 4 inches Weight = 94.5 pounds BMI = 16.3 kg/m
Anthropometric Measurements: • Triceps Skin Fold Thickness = 11.3mm (normal 16.5mm) • Mid-arm circumference = 23.6 cm (normal 28.5cm) • Waist – to – Hip Circumference Ratio = 52 / 72 = 0.72
Systemic Examination: • Abdomen • Chest • CVS • CNS Unremarkable
Provisional / Differential Diagnosis: • Gastro Esophageal Reflux Disease • AchalasiaCardia • Hiatus Hernia
Investigations: Complete Blood Picture: • Hemoglobin: 14.7g/dl • Hematocrit: 42.5% • TLC: 9.0 x 10 / L • Platelets: 259 x 10 / L ESR: • 25mm in 1st hour
Liver Function Tests: • Bilirubin: 0.6 • ALP: 73 Renal Function Tests: • Blood Urea Nitrogen: 20 • Creatinine: 0.5 PT / APTT: 14 / 35
ECG ECHOCARDIOGRAPHY X- RAY NORMAL STUDY
Radiologic Investigations: • Chest X- Ray • Ultrasound Abdomen and Pelvis • Barium Swallow • CT Abdomen
Ultrasound Abdomen & Pelvis: No pathology detected sonographically. Barium Meal study was advised to rule out APD or GERD.
Barium Meal Study: Stomach: Normal site, size and shape No ulcer or filling defect Duodenum: Duodenal cap well outlined
Gastroenterology Consultation: • Upper GI Endoscopy • Esophageal Function Tests • Medical / Conservative Treatment
Upper GI Endoscopy: Esophagus: Patulous Lower Esophageal Sphincter Stomach: Gastroesophageal Reflux Duodenum Normal study
Histopathology of Gastric Mucosa: Helicobacter Pylori associated Chronic Mild Gastritis