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Target. Transactivator. X. Mouse with Floxed BMPRII. TRE-P min CMV. CRE. SM 22 a. tTA. SM22 -tTA + /Cre +. CRE. CRE. TRE-P min CMV. TRE-P min CMV. tTA. SM 22 a. exon 4 exon 5. Frt LoxP LoxP. SM 22 a. tTA. Doxycycline. Frt LoxP.
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Target Transactivator X Mouse with Floxed BMPRII TRE-PminCMV CRE SM 22a tTA SM22-tTA+/Cre+ CRE CRE TRE-PminCMV TRE-PminCMV tTA SM 22a exon 4 exon 5 Frt LoxP LoxP SM 22a tTA Doxycycline Frt LoxP Mouse with conditionally deleted BMPRII in SMC X