Evalon Vaginal Cream (Generic Estriol Vaginal Cream)

1. Evalon Vaginal Cream (Generic Estriol Vaginal Cream) © All Contraceptives

2. Evalon Vaginal Cream (Generic Estriol Vaginal Cream) Evalon Vaginal Cream (Estriol Vaginal Cream) is used to relieve Vaginal Dryness (Atrophic Vaginitis),Pruritus vulvae, Dyspareunia due to vulvo-vaginal atrophy, vaginal infections, vaginal itching and irritation. It is also used as pre-operative therapy for vulvo-vaginal surgery and during subsequent convalescence. It may take several days or weeks before you notice an improvement. © All Contraceptives

3. Evalon Vaginal Cream (Generic Estriol Vaginal Cream) Active Ingredient The active pharmaceutical ingredients contained in Evalon Vaginal cream is Estriol. Each gram of Evalon Vaginal cream contains 1 mg of Estriol. © All Contraceptives

4. Evalon Vaginal Cream (Generic Estriol Vaginal Cream) Chemical Structure - Estriol © All Contraceptives

5. Evalon Vaginal Cream (Generic Estriol Vaginal Cream) Evalon Vaginal Cream Evalon Vaginal Cream is manufactured by Aspen in Germany. It is marketed by Sandoz Private Limited, India. (Website: https://www.sandoz.com/) URL: URL: https://www.allcontraceptives.com/estradiol-vaginal-cream.html https://www.allcontraceptives.com/estradiol-vaginal-cream.html © All Contraceptives

6. Evalon Vaginal Cream (Generic Estriol Vaginal Cream) Uses of Evalon Vaginal cream When your body is in short supply of Estrogens, replacing it can ease the uncomfortable changes that occur in the vagina, vulva (female genitals), and urethra (part of the urinary system). Conditions that are treated with vaginal estrogens like Evalon Vaginal Cream include a genital skin condition (vulvar atrophy), inflammation of the vagina (atrophic vaginitis), and inflammation of the urethra (atrophic urethritis). Estrogens work partly by increasing a normal clear discharge from the vagina and making the vulva and urethra healthy. Using or applying an estrogen relieves or lessens: Dryness and soreness in the vagina, Itching, redness, or soreness of the vulva, Feeling an urge to urinate more often then is needed or experiencing pain while urinating and Pain during sexual intercourse. © All Contraceptives

7. Evalon Vaginal Cream (Generic Estriol Vaginal Cream) Recommended Dosage The dosage of Evalon Vaginal Cream Evalon Vaginal Cream (Generic Estriol Vaginal Cream) for various indications is given below: Atrophic vaginitis: For starting and continuation of treatment of postmenopausal symptoms, the lowest effective dose for the shortest possible duration should be used. The normal dose is one applicator- dose (0.5g cream containing 0.5mg Estriol) per day for 2 to 3 weeks. As maintenance dosage, one applicator-dose twice a week. Pre-surgery therapy: One applicator-dose per day should begin 2 weeks before the operation. Following surgery: The therapy should be resumed after a period of at least 2 weeks using one applicator-dose twice a week. URL: URL: https://www.allcontraceptives.com/estradiol-vaginal-cream.html https://www.allcontraceptives.com/estradiol-vaginal-cream.html © All Contraceptives

8. Evalon Vaginal Cream (Generic Estriol Vaginal Cream) Contraindications Evalon Cream (Estriol Vaginal Cream) is contraindicated in patients with the following conditions: Hypersensitivity to Estriol or any inactive component of this medication. Undiagnosed abnormal genital bleeding. Known or suspected pregnancy. Known, suspected, or history of cancer of the breast. Known or suspected estrogen-dependent neoplasia. Untreated endometrial hyperplasia. URL: URL: https://www.allcontraceptives.com/estradiol-vaginal-cream.html https://www.allcontraceptives.com/estradiol-vaginal-cream.html © All Contraceptives

9. Evalon Vaginal Cream (Generic Estriol Vaginal Cream) Contraindications Evalon Cream (Estriol Vaginal Cream) is contraindicated in patients with the following conditions: Active or recent (within the past year) arterial thromboembolic disease (for example, stroke, myocardial infarction). Known thrombophilic disorders (e.g. protein C, protein S, or antithrombin deficiency. Liver dysfunction or disease. Porphyria URL: URL: https://www.allcontraceptives.com/estradiol-vaginal-cream.html https://www.allcontraceptives.com/estradiol-vaginal-cream.html © All Contraceptives

10. Evalon Vaginal Cream (Generic Estriol Vaginal Cream) Storage Instructions Evalon Vaginal Cream (Generic Estriol Vaginal Cream) have to be stored at controlled room temperature i.e. from 20°C to 25°C (68°F to 77°F) with excursions permitted between 15° to 30°C (59° to 86°F). Keep this as well as all other medicines away from children and pets. URL: URL: https://www.allcontraceptives.com/estradiol-vaginal-cream.html https://www.allcontraceptives.com/estradiol-vaginal-cream.html © All Contraceptives

11. Evalon Vaginal Cream (Generic Estriol Vaginal Cream) Warnings HRT:Hormone Replacement Therapy (HRT) must only be started for symptoms that adversely affect quality of life. An appraisal of the risks and benefits must be undertaken at least each year. Medical History: Existing vaginal infections must be treated before therapy with Evalon cream is initiated. Patients with certain medical conditions including, leiomyoma or endometriosis, a history of or risk factors for thromboembolic disorders, hypertension, liver disorders, diabetes mellitus with or without vascular involvement, cholelithiasis, migraine or (severe) headache, systemic lupus erythematosus, a history of endometrial hyperplasia, epilepsy, asthma and otosclerosis, will need close supervision particularly when the condition is active, or has occurred previously and/or was aggravated during pregnancy or previous hormone treatment. URL: URL: https://www.allcontraceptives.com/estradiol-vaginal-cream.html https://www.allcontraceptives.com/estradiol-vaginal-cream.html © All Contraceptives

12. Evalon Vaginal Cream (Generic Estriol Vaginal Cream) Warnings Other conditions: Discontinue treatment if contraindicated, jaundice or a deterioration in liver function occurs, there is a significant increase in blood pressure, a new onset of migraine or pregnancy occurs. Breakthrough Bleeding: In case breakthrough bleeding or spotting occurs, the reason should be investigated. Patients with cardiac or renal dysfunction or hypertri-glyceridemia should be carefully observed. URL: URL: https://www.allcontraceptives.com/estradiol-vaginal-cream.html https://www.allcontraceptives.com/estradiol-vaginal-cream.html © All Contraceptives

13. Evalon Vaginal Cream (Generic Estriol Vaginal Cream) Effects On Ability To Drive And Use Machines There is no information to suggest that Evalon Cream (Estriol Vaginal Cream) affects a patient’s ability to drive or operate machinery. URL: URL: https://www.allcontraceptives.com/estradiol-vaginal-cream.html https://www.allcontraceptives.com/estradiol-vaginal-cream.html © All Contraceptives

14. Evalon Vaginal Cream (Generic Estriol Vaginal Cream) Side Effects The most frequent possible side effects of Evalon Vaginal Cream (Estriol Vaginal Cream) include include nausea and vomiting, breast tenderness or pain in the breasts, vaginal bleeding or spotting during or on withdrawal of therapy, excessive production of cervical mucous, headache, application site irritation and pruritus. URL: URL: https://www.allcontraceptives.com/estradiol-vaginal-cream.html https://www.allcontraceptives.com/estradiol-vaginal-cream.html © All Contraceptives

15. Evalon Vaginal Cream (Generic Estriol Vaginal Cream) Overdose Symptoms and Treatment The acute toxicity of Estriol in animals is very low. Symptoms of acute Evalon oral overdose are nausea, vomiting and possibly withdrawal bleeding in females. No specific antidote is known. If necessary a symptomatic treatment should be given. URL: URL: https://www.allcontraceptives.com/estradiol-vaginal-cream.html https://www.allcontraceptives.com/estradiol-vaginal-cream.html © All Contraceptives

16. Evalon Vaginal Cream (Generic Estriol Vaginal Cream) Evalon Vaginal Cream During Pregnancy Estriol Vaginal Cream (Evalon Vaginal Cream) has been classified by the US FDA as Pregnancy Category X. Animal studies conducted have proved that high doses of estrogens have produced urogenital malformations in the offspring. There are no adequate and well-controlled studies conducted in pregnant women. If pregnancy occurs during medication with Evalon Vaginal Cream, treatment should be withdrawn immediately. The results of most epidemiological studies to date relevant to inadvertent foetal exposure to estrogens indicate no teratogenic or foetotoxic effects. URL: URL: https://www.allcontraceptives.com/estradiol-vaginal-cream.html https://www.allcontraceptives.com/estradiol-vaginal-cream.html © All Contraceptives

17. Evalon Vaginal Cream (Generic Estriol Vaginal Cream) Evalon Vaginal Cream Evalon Vaginal Cream (Generic Estriol Vaginal Cream) is manufactured by manufactured by Aspen in Germany. It is marketed by Sandoz Private Limited, India. URL: URL: https://www.allcontraceptives.com/estradiol-vaginal-cream.html https://www.allcontraceptives.com/estradiol-vaginal-cream.html © All Contraceptives