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Introduction

FLUID LOSS DOES NOT EXPLAIN COAGULATION ACTIVATION DURING AIR TRAVEL. Q-FEVER ON SMALL SHEEP AND GOAT FARMS IN THE PROVINCE OF UTRECHT. J.G.M.H. Brendel 1 , A.J.M. Brandsen-Schreijer 1 , A.M.C. van Lier 1 , A. de Bruin 3 , S. Rutjes 3 , Y. de Geus 2 , W. van der Hoek 4 .

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Introduction

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  1. FLUID LOSS DOES NOT EXPLAIN COAGULATION ACTIVATION DURING AIR TRAVEL Q-FEVER ON SMALL SHEEP AND GOAT FARMS IN THE PROVINCE OF UTRECHT J.G.M.H. Brendel1 , A.J.M. Brandsen-Schreijer1, A.M.C. van Lier1, A. de Bruin3, S. Rutjes3, Y. de Geus2, W. van der Hoek4. 1 The Municipal Health Service (GGD) Midden Nederland, Zeist, the Netherlands 2 Veterinary Health Clinic Krommerijnstreek, Schalkwijk, the Netherlands 3 Laboratory for Zoonoses and Environmental Microbiology National Institute for Public Health and the Environment, (Rijksinstituut voor Volksgezondheid en Milieu, RIVM), Bilthoven, the Netherlands 4 Centre for Infectious Disease Control, RIVM Bilthoven, the Netherlands Introduction In the province of Utrecht, 124 human Q fever cases were reported in 2009. Large farms with dairy goats seemed to be the main source for Q-fever, but the role of smaller farms (about 2000 in the province of Utrecht) was unclear. • Results • Eight (17.8%) of the farms (mainly sheep) were located within the 5 km range of a large bulk milk-positive dairy goat farm. • Pooled milk samples of 3 farms tested positive (6,7%; 95CI:1.4-18.3), none within the 5 km zone. • On 5 farms there was a history of human Q-fever among residents (11%; 95CI: 3.7-24.1): • one farm within the five km zone and one farm with a positive milk sample. • The presence of a goat on the farm increased the risk of testing positive (RR 10,9; 95CI: 1.1-104.2) Aim To study the prevalence of O-fever in pooled milk samples from small farms with sheep and goats in the province of Utrecht. • Methods • Prevalence study • 45 Farms (less then 50 goats or sheep) participated. • Milk samples were collected of 10 animals per farm. • Analysis was done by a multiplex real-time PCR (genomic targets com1 and IS1111). • Questionnaire concerning the number of animals, abortion rate and Q-fever diagnosis amongst the farmer or his relatives. Figure 1: incidence of Q-fever in the province of Utrecht 2009 Incidence: Q-fever patients per 100.000 inhabitants Conclusion We conclude that the number of small farms positive for Q-fever in the province of Utrecht is small, with an increased risk for farms keeping goats.

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