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Chagas Disease

Chagas Disease. Sarah Anderson BIOL 402. http://www.dndi.org/diseases/chagas/disease-background.html. http://www.cdc.gov/parasites/chagas/diagnosis.html. http://www.cdc.gov/parasites/chagas/gen_info/vectors/index.html. Overview. http://www.treatchagas.org/cp_chagas_background.aspx.

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Chagas Disease

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  1. Chagas Disease Sarah Anderson BIOL 402 http://www.dndi.org/diseases/chagas/disease-background.html http://www.cdc.gov/parasites/chagas/diagnosis.html http://www.cdc.gov/parasites/chagas/gen_info/vectors/index.html

  2. Overview http://www.treatchagas.org/cp_chagas_background.aspx http://www.dndi.org/diseases/chagas/global-view.html http://www.who.int/mediacentre/factsheets/fs340/en/index.html

  3. T. cruzi Teixeira, A.R. et.a. “Pathogenesis of chagas’ disease: aparasite persistence and autoimmunity” Clin. MicrobiolRev. 2011 Jul. 24 http://www.tulane.edu/~wiser/protozoology/notes/kinet.html

  4. Life Cycle: Transmission http://www.tulane.edu/~wiser/protozoology/notes/kinet.html#forms http://www.cdc.gov/parasites/chagas/gen_info/vectors/index.html

  5. Life Cycle: T. cruziinfects cells Fernandes, M. C. et. al. “Trypanosomacruzisubverts the sphingomyelinase-mediated plasma membrane repair pathway.” J Exp Med. 2011 May 2. http://www.nature.com/nrmicro/journal/v9/n7/full/nrmicro2597.html

  6. Life Cycle: Morphological Forms Epimastigote: Amastigote: Trypomastigote: http://www.tulane.edu/~wiser/protozoology/notes/kinet.html#forms

  7. Chagas Disease: Symptoms • Acute Stage • Chronic stage http://www.cdc.gov/parasites/chagas/disease.html http://www.ncbi.nlm.nih.gov/books/NBK62523/ Teixeira, A.R. et.a. “Pathogenesis of chagas’ disease: aparasite persistence and autoimmunity” Clin. Microbiol Rev. 2011 Jul. 24 http://www.dndi.org/diseases/chagas.html

  8. Chagas Disease: Diagnosis Diagnosis can be difficult http://www.cdc.gov/parasites/chagas/diagnosis.html Teixeira, A.R. et.a. “Pathogenesis of chagas’ disease: aparasite persistence and autoimmunity” Clin. Microbiol Rev. 2011 Jul. 24 http://www.ncbi.nlm.nih.gov/books/NBK62523/

  9. Chagas Disease: Treatment Benznidazole: Nifurtimox: http://thematthewsstory.com/2010/10/20/got-ahold-of-bayer/thumb/ http://papabolivia.blogspot.com/p/health-and-medicine.html Wilkinson, S. R. et. al. A mechanism for cross-resistance to nifurtimox and benznidazole in trypanosomes. PNAS. 2008 Apr. 1. 5022-5027 Teixeira, A.R. et.a. “Pathogenesis of chagas’ disease: aparasite persistence and autoimmunity” Clin. Microbiol Rev. 2011 Jul. 24

  10. Chagas Disease: Prevention http://www.ncbi.nlm.nih.gov/books/NBK62523/#appendixes.app1.21.s7 http://www.cgdev.org/section/initiatives/_archive/millionssaved/studies/case_12

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