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CHAPTER 13: Renal Transplantation. Rosnawati Yahya Goh Bak Leong Fan Kin Sing Rohan Malek Bin Dato’ Dr. Johan S. Prasad Menon Tan Si Yen Wong Hin Seng. Source: 21 st MDTR Report 2013, NRR. Table 13.1.1: Stock and flow of renal transplantation, 2004-2013.
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CHAPTER 13:Renal Transplantation Rosnawati Yahya Goh Bak Leong Fan Kin Sing Rohan Malek Bin Dato’ Dr. Johan S. Prasad Menon Tan Si Yen Wong Hin Seng Source: 21st MDTR Report 2013, NRR
Table 13.1.1: Stock and flow of renal transplantation, 2004-2013 Source: 21st MDTR Report 2013, NRR
Figure 13.1.1: Stock and flow of renal transplantation, 2004-2013 New patients Functioning graft at 31st Dec 2,000 1,800 1,600 1,400 1,200 No. of patients 1,000 800 600 400 200 0 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 Year Source: 21st MDTR Report 2013, NRR
Table 13.1.2: New transplant rate per million population (pmp), 2004-2013 Source: 21st MDTR Report 2013, NRR
Figure 13.1.2: New transplant rate, 2004-2013 Source: 21st MDTR Report 2013, NRR
Table 13.1.3: Transplant prevalence rate per million population (pmp), 2004-2013 Source: 21st MDTR Report 2013, NRR
Figure 13.1.3: Transplant prevalence rate, 2004-2013 Source: 21st MDTR Report 2013, NRR
Table 13.1.4: Place of transplantation, 2004-2013 Source: 21st MDTR Report 2013, NRR
Figure 13.1.4(a): Places of transplantation, 2004-2013 Source: 21st MDTR Report 2013, NRR
Figure 13.1.4(b): Place of transplantation within Malaysia Source: 21st MDTR Report 2013, NRR
Table 13.2.1: Renal transplant recipients’ characteristics, 2004-2013 Source: 21st MDTR Report 2013, NRR
Table 13.2.2: Primary causes of end stage renal failure, 2004-2013 Source: 21st MDTR Report 2013, NRR
Table 13.3.1: Type of renal transplantation, 2004-2013 *Commercial Cadaver (China, India, other oversea) *Commercial live donor (living unrelated) *Cadaver (local) Source: 21st MDTR Report 2013, NRR
Table 13.3.2: Biochemical data, 2009-2013 Source: 21st MDTR Report 2013, NRR
Table 13.3.3: Immunosuppressive Medications, 2009-2013 Source: 21st MDTR Report 2013, NRR
Table 13.3.4: Non-immunosuppressive medications, 2009-2013 Source: 21st MDTR Report 2013, NRR
Table 13.4.1: Post-transplant complications, 2009-2013 *Hypertension: BP systolic >140 and BP diastolic >90 or have either Beta blocker/ Calcium channel blocker / ACE inhibitor / AIIRB / Other anti-hypertensive Source: 21st MDTR Report 2013, NRR
Table 13.4.2: Transplant patient death rate and graft loss, 2004-2013 *Graft loss=graft failure *All losses=death / graft loss (acute rejection happens concurrently with graft failure / death) Source: 21st MDTR Report 2013, NRR
Figure 13.4.2(a): Transplant recipient death rate, 2004-2013 Source: 21st MDTR Report 2013, NRR
Figure 13.4.2(b): Transplant recipient graft loss rate, 2004-2013 Source: 21st MDTR Report 2013, NRR
Table 13.4.3: Causes of death in transplant recipients, 2004-2013 Source: 21st MDTR Report 2013, NRR
Table 13.4.4: Causes of graft failure, 2004-2013 Source: 21st MDTR Report 2013, NRR
Table 13.5.1(a): Patient survival, 2004-2013 *n=Number at risk SE=standard error Source: 21st MDTR Report 2013, NRR
Figure 13.5.1(a): Patient survival, 2004-2013 Source: 21st MDTR Report 2013, NRR
Table 13.5.1(b): Risk factors for transplant patient survival 2004-2013 Source: 21st MDTR Report 2013, NRR
Table 13.5.2(a): Graft survival, 2004-2013 *n=Number at risk SE=standard error Source: 21st MDTR Report 2013, NRR
Figure 13.5.2(a): Graft survival, 2004-2013 Source: 21st MDTR Report 2013, NRR
Table 13.5.2(b): Risk factors for transplant graft survival 2004-2013 Source: 21st MDTR Report 2013, NRR
Table 13.5.3: Unadjusted patient survival by type of transplant, 2004-2013 *n=Number at risk SE=standard error Source: 21st MDTR Report 2013, NRR
Figure 13.5.3: Patient survival by type of transplant, 2004-2013 Source: 21st MDTR Report 2013, NRR
Table 13.5.4: Graft survival by type of transplant, 2004-2013 *n=Number at risk SE=standard error Source: 21st MDTR Report 2013, NRR
Figure 13.5.4: Graft survival by type of transplants, 2004-2013 Source: 21st MDTR Report 2013, NRR
Table 13.5.5(a): Patient survival by year of transplant (Living related transplant, 2004-2013) *n=Number at risk SE=standard error Source: 21st MDTR Report 2013, NRR
Figure 13.5.5(a): Patient survival by year of transplant (Living related transplant, 2004-2013) Source: 21st MDTR Report 2013, NRR
Table 13.5.5(b): Graft survival by year of transplant (Living related transplant, 2004-2013) *n=Number at risk SE=standard error Source: 21st MDTR Report 2013, NRR
Figure 13.5.5(b): Graft survival by year of transplant (Living related transplant, 2004-2013) Source: 21st MDTR Report 2013, NRR
Table 13.5.6(a): Patient survival by year of transplant (Commercial cadaver transplant, 2004-2013) *n=Number at risk SE=standard error Source: 21st MDTR Report 2013, NRR
Figure 13.5.6(a): Patient survival by year of transplant (Commercial cadaver transplant, 2004-2013) Source: 21st MDTR Report 2013, NRR
Table 13.5.6(b): Graft survival by year of transplant (Commercial cadaver transplant, 2004-2013) *n=Number at risk SE=standard error Source: 21st MDTR Report 2013, NRR
Figure 13.5.6(b): Graft survival by year of transplant (Commercial cadaver transplant, 2004-2013) Source: 21st MDTR Report 2013, NRR
Table 13.6.1: Risk factors for IHD in renal transplant recipients at year 2009-2013 **Hypertension: BP systolic > 140 and BP diastolic > 90 OR have either Beta blocker / Calcium channel blocker / ACE inhibitor / AIIRB / Other anti-hypertensive drugs GFR (mL/min/1.73m2) = 1.2*(140-age(year))*weight(kg) / creatinine (µmol/L) if male GFR (mL/min/1.73m2) = 0.85*(1.2*(140-age(year))*weight(kg) / creatinine (µmol/L) if female CKD stage III-GFR, 30-60 CKD stage IV-GFR, 15-30 CKD stage V-GFR, <15 Source: 21st MDTR Report 2013, NRR
Figure 13.6.1(a): Venn diagram for pre and post transplant complications (in %) at year 2009 10.4 29.6 1.2 5.6 1.8 40.9 10.5 DM HPT CKD Source: 21st MDTR Report 2013, NRR
Figure 13.6.1(b): Venn diagram for pre and post transplant complications (in %) at year 2010 CKD 10.1 30.5 1.4 6.5 2.2 37.7 11.7 DM HPT Source: 21st MDTR Report 2013, NRR
Figure 13.6.1(c): Venn diagram for pre and post transplant complications (in %) at year 2011 CKD 8.7 29.5 1.8 6.1 2.2 39.3 12.5 HPT DM Source: 21st MDTR Report 2013, NRR
Figure 13.6.1(d): Venn diagram for pre and post transplant complications (in %) at year 2012 CKD 13.1 28 1.9 6.1 2.1 36.5 12.4 HPT DM Source: 21st MDTR Report 2013, NRR
Figure 13.6.1(e): Venn diagram for pre and post transplant complications (in %) at year 2013 CKD 12.3 29.8 1.6 6.2 2.6 37 10.5 DM HPT Source: 21st MDTR Report 2013, NRR
Table 13.6.2(a): Systolic BP, 2009-2013 Source: 21st MDTR Report 2013, NRR
Figure 13.6.2(a): Systolic BP, 2009-2013 Systolic BP <120 Systolic BP 120-129 Systolic BP 130-139 Systolic BP 140-159 Systolic BP 160-179 Systolic BP >=180 100 80 60 Percent 40 20 0 2009 2010 2011 2012 2013 Year Source: 21st MDTR Report 2013, NRR
Table 13.6.2(b): Diastolic BP, 2009-2013 Source: 21st MDTR Report 2013, NRR
Figure 13.6.2(b): Diastolic BP, 2009-2013 Diastolic BP <80 Diastolic BP <85 Diastolic BP 85-89 Diastolic BP 90-99 Diastolic BP 100-109 Diastolic BP >=110 100 80 60 Percent 40 20 0 2009 2010 2011 2012 2013 Year Source: 21st MDTR Report 2013, NRR