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Severity of illness (APACHE II score ≥ 25) stratified by RIFLE category in septic shock

Severity of illness (APACHE II score ≥ 25) stratified by RIFLE category in septic shock. 80. 69.9. 70. 58.6. 60. 45.2. 50. APACHE II Score >25 (%). 40. 28.3. 30. 20. 10. 0. None. Risk. Injury. Failure. RIFLE Category. Bagshaw et al, Intensive Care Med, 2009:35:871-881. 100.

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Severity of illness (APACHE II score ≥ 25) stratified by RIFLE category in septic shock

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  1. Severity of illness (APACHE II score ≥ 25) stratified by RIFLE category in septic shock 80 69.9 70 58.6 60 45.2 50 APACHE II Score >25 (%) 40 28.3 30 20 10 0 None Risk Injury Failure RIFLE Category Bagshaw et al, Intensive Care Med, 2009:35:871-881

  2. 100 80 Bagshaw et al, Intensive Care Med, 2009:35:871-881 90 75 80 70 70 65 60 60 Cumulative effective Antimicrobial Therapy 50 Incidence AKI (%) 40 55 30 50 20 45 10 40 0 <1 1-2 2-3 3-12 12-24 >24 Time from Hypotension Onset (hrs) Antimicrobial Therapy AKI Cumulative effective antimicrobial therapy following onset of hypotension and associated incidence of AKI.

  3. Crude survival for septic shock patients stratified by severity of AKI. 1.00 0.75 Survival Probability 0.50 0.25 Log-rank, p<0.0001 0.00 0 20 40 60 80 100 Time (Days) No AKI RIFLE: Risk RIFLE: Injury RIFLE: Failure Bagshaw et al, Intensive Care Med, 2009:35:871-881

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