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P-I k B a

A. B. H-7 (µM). staurosporine (µM). - - 5 10 15 30. - - 0.03 0.1 0.2 0.4. P-I k B a. a -tubulin. - A4 A4 A4 A4 A4. - A4 A4 A4 A4 A4. C. D. E. F. 48/80 (µM). U-73122 (µM). AG 18 (µM). genistein (µM).

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P-I k B a

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  1. A B H-7 (µM) staurosporine (µM) - - 5 10 15 30 - - 0.03 0.1 0.2 0.4 P-IkBa a-tubulin - A4 A4 A4 A4 A4 - A4 A4 A4 A4 A4 C D E F 48/80 (µM) U-73122 (µM) AG 18 (µM) genistein (µM) - - 1 6 - - 12.5 25 - - 120 160 - - 10 60 P-IkBa a-tubulin - A4 A4 A4 - A4 A4 A4 - A4 A4 A4 - A4 A4 A4 G H I J GDPb (mM) GF 109203X (µM) suramin (mM) LY294002 (µM) - - 2 12 - - 0.2 0.4 - - 0.1 0.3 - - 50 P-IkBa a-tubulin - A4 A4 A4 - A4 A4 A4 - A4 A4 A4 - A4 A4

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