B. Dongmo Nguimfack AMDS TCO Unit/HIV, WHO

1. B. Dongmo NguimfackAMDS TCO Unit/HIV, WHO Global Price Reporting Mechanism (GPRM); ARV Drug Regulatory Status Database (DRS); ARV Active Pharmaceutical Ingredients Survey Data (API): relevance and options for the future

2. What is AMDS • The AMDS is a network of technical partner organisations that work to support countries in procurement and supply management of HIV commodities. The secretariat of this network is housed in WHO/HIV Department. • The AMDS operates as a clearing house, collecting and disseminating strategic information: Prices, availability and regulatory status of ARVs, technical information of HIV diagnostics and other HIV-related health supplies(http://www.who.int/hiv/amds/en/)

3. AMDS Clearing House: AMDS Information Platform PQ (EMP) Regula-tory status Fore-casting portal (surveys, back-ground, papers) Treat-ment guide-lines repo-sitory API Global Price Repor-ting Mecha-nism Opioïd Sub-stitution Therapy data-base Capacity building tools: PSM Toolbox HTM Corpo- rate Pricing Policies (MSF) HTM HTM H H H HT H H

4. GPRM: background - current use

5. GPRM: background - current use

6. GPRM: background - current use • Screenshot of data export ABC + 3TC 60 + 30 mg here

7. GPRM: background - current use • Screenshot data export facility opening page

8. GPRM: background - current use • Screenshot of excel ABC + 3TC 60 + 30 mg

9. GPRM: Limitations • Data from 80 countries and 2492 transactions in 2014 – but only public sector procurement (PEPFAR supported, GFATM supported, + UNICEF, IDA, UNITAID, CHAI, MISSIONPHARMA, WHO CPS) • Time lag: quarterly reporting by data providers and reporting delay from their data suppliers makes delay unavoidable. • Low frequency procurement (<5 transactions), donations (0 price) and transactions of which price is (can)not (be) communicated is not visible. • Bias toward good procurement practices. • Limited public visibility.

10. GPRM: How we used it Summary report Country profile reports • Data provision to other reports • UA report • MIC report • Data on volumes sold / trends to produce annual forecast of future demand (with UNAIDS, SCMS, FUTURES INSTITUTE, CHAI, GFATM) (triangulation with ARV survey) • Publicized it to programme and supply managers: • I+ Solutions, UNDP, EMP staff workshops • AMD newsletter

11. GPRM: Impact • Anecdotal reports that country supply managers are using the GPRM • Procurement partners use it to assess own performance • Use in academic papers

12. GPRM: Imagine you wanted to access the GPRM - you need to be persistent - we need to be smarter in our referencing Imagine you wanted to access the GPRM: • You go to the WHO website • You search for "GPRM" - you find it – it is on the first line in your search, but you have to go down all the way to the bottom of the landing page to access it • You search for "prices of HIV medicines" – you don't find it - you end up on the EMP website where the existence of a 2005 document is publicized and where you find a link to the 2013 edition of "Untangling the web…" • You search for "price of AIDS drugs" – you might find it if you are really persistent • You go to Google – "price of AIDS drugs" – you will not find it in the first 5 screens (but will find the EMP page) • You go to Yahoo - "price of HIV medicines" - you will not find it in the first 5 screens (but will find the EMP page)

13. ARV Drug Regulatory Status Database (DRS) • Screenshot here

14. ARV Drug Regulatory Status Database (DRS) • Uses: • Emergency procurement • Civil society: Accountability of manufacturers • Legal uses: provides prima facie evidence of availability of ARVs • Limitations • Manufacturers derived data • Only PQ's and stringently regulated products – domestic products which don't comply with GFATM quality standards are not included • Limited public visibility

15. ARV Active Pharmaceutical Ingredients Survey Data (API)

16. What could be done more? • Expand to other therapeutic areas • TB, Malaria • Hepatitis • Reproductive health • Expand to diagnostics • Better WEB and internet referencing • Link different databases - perhaps also to those external to WHO • Increase reporting on domestic procurement in GPRM or related database • Automate country profile production (and publicize it on WEB?) • Publicize in peer review papers

17. URL for the different databases Global Price ReportingMechanism (GPRM): http://www.who.int/hiv/amds/price/hdd/ The Drug RegulatoryStatusDatabase: http://www.who.int/hiv/amds/patents_registration/drs/ Country profile https://www.dropbox.com/home/Country%20Profilesemail:amds@who.intpassword:AMDSHIVWHO PSM Toolboxwebsite: http://psmtoolbox.org/en/ SOURCES AND PRICES OF ACTIVE PHARMACEUTICAL INGREDIENTS http://www.who.int/hiv/amds/api.pdf ControlledMedicines: http://www.who.int/entity/hiv/amds/ControlledMedicineDatabase.xls Forecasting antiretroviral demand: http://www.who.int/hiv/amds/forecasting/en/index.html

18. Boniface Dongmo Nguimfackdongmonguimfackb@who.intGlobal Price ReportingMechanism (GPRM)The Drug RegulatoryStatusDatabaseSOURCES AND PRICES OF ACTIVE PHARMACEUTICAL INGREDIENTSControlledMedicinesSummary report from the Global Price ReportingMechanismCountry Procurement ProfilesVincent Habiyamberehabiyamberev@who.intPSM ToolboxForecasting antiretroviral demandARV use survey Contacts

19. http://apps.who.int/hiv/amds/price/hdd/