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HSCI 330. Exploratory Strategies in Epidemiology. Week 1 – Lecture Goals Introduce instructor Overview of course Introduction of WebCT site Review syllabus (Register i>Clickers) Week 1 learning objectives. Broad issues in epidemiological analysis to be covered in HSCI 330.
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HSCI 330 Exploratory Strategies in Epidemiology
Week 1 – Lecture Goals Introduce instructor Overview of course Introduction of WebCT site Review syllabus (Register i>Clickers) Week 1 learning objectives
Broad issues in epidemiological analysis to be covered in HSCI 330 What is the study question? How should the study variables be measured? How should the study be designed? What measures of disease frequency and effect should be used? What kinds of bias are likely?
Learning objective 2. In research synopsis or real research paper, describe: E – Exposure Variable D – Disease Variable C – Control Variable
Learning objective 2. In research synopsis or real research paper, describe: E – Exposure Variable (Determinant) D – Disease Variable (Outcome) C – Control Variable (Choose variables that are known determinants of the outcome.)
E=0 E=1 Swam Did not swim D=0, No illness D=1, Illness
E=0 E=1 Swam Did not swim D=0, No illness D=1, Illness C=1, Old age
Control variables: Choose control variables that are known determinants of the outcome (D).
E=0 E=1 E=2 Swam <= 2 hours Swam > 2 hours Did not swim D=0, No illness D=1, Illness
Continuous versus categorical variables Categorical: Didn’t swim, swam<=2hrs, swam>2hrs Continuous: Time spent swimming (minutes) Examples: 0.0 minutes, 134.3 minutes.
i>Clicker QuickCheck In the Sydney Beach Users study, exposure was alternatively defined by distinguishing those who swam in polluted water from those who swam in non-polluted water and from those who did not swim at all. Based on this scenario, fill in the missing information in the following statement: The exposure variable is a _____ variable. Continuous Categorical I don’t know
i>Clicker QuickCheck In the Sydney Beach Users study, exposure was alternatively defined by distinguishing those who swam in polluted water from those who swam in non-polluted water and from those who did not swim at all. Based on this scenario, fill in the missing information in the following statement: 2. The exposure variable has _____ categories. 2 3 4 5 I don’t know
i>Clicker QuickCheck In the Sydney Beach Users study, exposure was alternatively defined by distinguishing those who swam in polluted water from those who swam in non-polluted water and from those who did not swim at all. Based on this scenario, fill in the missing information in the following statement: 3. The exposure variable has 3 categories, on of which is _____. did not swim polluted water swam water not polluted I don’t know
i>Clicker QuickCheck In the Sydney Beach Users study, the illness outcome was whether or not an acute infectious illness developed 1 week after swimming at the beach. Also, in addition to age, another control variable was whether or not a study subject swam on days other than the day he or she was interviewed. Which of the following choices is not a control variable: age swimming status on other days swimming status on day of interview I don’t know