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Pedigree Analysis

Pedigree Analysis. Goals of Pedigree Analysis. 1. Determine the mode of inheritance: autosomal dominant & recessive, sex-linked, etc. 2. Determine the probability of an affected offspring for a given cross. Basic Symbols. More Symbols. Nondisjunction.

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Pedigree Analysis

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  1. Pedigree Analysis

  2. Goals of Pedigree Analysis • 1. Determine the mode of inheritance: autosomal dominant & recessive, sex-linked, etc. • 2. Determine the probability of an affected offspring for a given cross.

  3. Basic Symbols

  4. More Symbols

  5. Nondisjunction • the failure of one or more pairs of homologous chromosomes or sister chromatids to separate normally during meiosis – uneven distribution of chromosomes in eggs or sperm.

  6. Autosomal Recessive Pedigree for blue eyes

  7. Autosomal Dominant

  8. Recessive Sex-Linked • Draw for DMD

  9. Dominant Sex-Linked Traits

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