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Microarray study design, example 3: Dye-Swap experiments

Good microarray projects require many experiments and careful design of the study as indicated in the publication shown below.

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Microarray study design, example 3: Dye-Swap experiments

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  1. Good microarray projects require many experiments and careful design of the study as indicated in the publication shown below

  2. Microarray study design, example 1: comparison against different control samples (Ctl; control, e.g., a RNA derived from an unstimulated cell line; Ref; common reference, e.g. a pool of RNA derived from healthy donors)

  3. Microarray study design, example 2: direct comparison of gene expression between two samples (a) or comparison of gene expression of the two samples (T, C) against a common reference (R) control sample.

  4. Microarray study design, example 3: Dye-Swap experiments

  5. Microarray study design, example 4: Variance and numbers of required experiments depending on the design of the study

  6. Microarray study design, example 5: Potential design of time course experiments

  7. Microarray study design, example 6: replicate experiments are mandatory to achieve significant results

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