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Oligo PRO ™ System: Quoting, Consumables

Oligo PRO ™ System: Quoting, Consumables. ssDNA/ssRNA Oligonucleotide Analysis Reagents. DN-415-0250 Oligel ™ ssDNA/ssRNA Gel, 250 mL Patented formula specifically designed for use with Oligo PRO™ DN-465-1000 Oligel™ Buffer, 1000 mL Inlet buffer used during separation

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Oligo PRO ™ System: Quoting, Consumables

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  1. Oligo PRO™ System: Quoting, Consumables

  2. ssDNA/ssRNA Oligonucleotide Analysis Reagents • DN-415-0250 Oligel™ ssDNA/ssRNA Gel, 250 mL • Patented formula specifically designed for use with Oligo PRO™ • DN-465-1000 Oligel™ Buffer, 1000 mL • Inlet buffer used during separation • DN-475-1000 Capillary Conditioning Solution, 1000 mL • Proprietary solution for eliminating EOF in capillary array (used weekly or periodically to restore separation performance) • DN-400-0001 Oligonucleotide OQ Standard 10X Solution, 1 mL • Used when performing operational qualification of system. Mixture of 19,20-mer 39,40-mer 59,60-mer polydT Consumable reagents generate a consistent recurring revenue stream

  3. dsRNA Duplex Native Gel Analysis Reagents • DN-515-0250 Native Oligel™, 250 mL • Non-denaturing formula specifically designed for use with Oligo PRO™ • Urea-free formula to avoid disrupting structure • Resolution optimized for < 60-mer • DN-465-1000 Native Oligel™ Buffer, 1000 mL • Inlet buffer used during native gel separation • Higher ionic strength to tolerate increased salts in sample • DN-475-1000 Capillary Conditioning Solution, 1000 mL • Proprietary solution for eliminating EOF in capillary array (used weekly or periodically to restore separation performance) • DN-400-0001 Native Oligel™ OQ Standard 10X Solution, 1 mL • Used when performing operational qualification of system. Mixture of 19,20-mer 39,40-mer polydT

  4. Quoting the Oligo PRO™ 96XT System Native Oligel reagents and shorter capillary array (40/63) should be quoted if application is dsRNA duplex analysis

  5. Quoting the Oligo PRO™ 24HT System Native Oligel reagents should be quoted if application is dsRNA duplex analysis

  6. Excel-Based Cost/Sample Calculator • Run different sample throughputs to see cost/sample • Higher throughput = lower cost/sample • Similar calculator for Native Gel dsDNA analysis CONFIDENTIAL

  7. Cost Per Sample: 96-Capillary Cartridge • Calculation assumes cost per capillary array = $5850 USD - $550 USD trade-in = $5300 USD • Proper maintenance and storage of capillary arrays can dramatically increase lifetime!! CONFIDENTIAL

  8. Capillary Array Cartridge Docking Station Accessory • Optional accessory for high throughput operations • Utilized for flushing capillary arrays off-line from the Oligo PRO™ system • Capable of generating up to 500 psi pressure to the array • Can be used for short term storage of idle capillary arrays in between use, allowing quick access to a back-up array. • Benefits of the docking station: • Unplug and/or recondition blocked capillaries to extend array lifetime • Avoid lengthy returns of arrays for factory servicing • Prime a back-up capillary array for immediate replacement to reduce downtime CONFIDENTIAL

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