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急診護理個案討論. 新光醫院 急診科 張志華 醫師. 2005 / 09 / 15. Hyperkalemia. 常考!. Hyperkalemia. Symptoms Generalized fatigue Weakness Paresthesias Paralysis Palpitations. Nonspecific !. Hyperkalemia. 考題!. Etiology Acute or chronic renal failure Crush injuries (rhabdomyolysis), burns
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急診護理個案討論 新光醫院 急診科 張志華醫師 2005 / 09 / 15
Hyperkalemia 常考!
Hyperkalemia • Symptoms • Generalized fatigue • Weakness • Paresthesias • Paralysis • Palpitations Nonspecific!
Hyperkalemia 考題! • Etiology • Acute or chronic renal failure • Crush injuries (rhabdomyolysis), burns • Foods (eg, bananas, oranges, high-protein diets, tomatoes, salt substitutes) • Redistribution: Acidosis, insulin deficiency, beta-blocker, acute digoxin overdose, succinylcholine, periodic paralysis (PP) • Drugs – slow-K, spirinolactone diuretics, NSAIDs
Hyperkalemia • Mild: 5.5-6.5 mEq/L • peaked T waves • Moderate: 6.5-7.5 mEq/L • prolonged PR interval • decreased P wave • ST depression or elevation • slight widening of the QRS
Hyperkalemia (cont.) • Severe: 7.5-8.5 mEq/L • wide QRS • flat and wide P waves • VPCs • Life-threatening: >8.5 mEq/L • loss of P • AV blocks • VT / VF • sinusoid patern
Hyperkalemia • Specific management: "See BIG Potassium Drop" • Calcium • Bicarbonate • Insulin and Glucose • Kayexalate • Dialysis 考題!
Hyperkalemia • General management: • Continuous ECG monitoring • DC K-sparing drugs (ACEI, spirinolactone) • DC high-K foods
Calcium • Stabilize cell membrane • Calcium gluconate 10%, 10 ml over 2-5 min • 2nd dose after 5 min if no response • Effect occurs in minutes and lasts for 1 hour • Further calcium ineffective unless hypocalcemia exists • Digoxin Toxicity contraindication !
Bicarbonate • Shift K+ to intracellular • 3 amp Jusomine IV over 5 min • May repeat q10-15 min • Onset in 30 min; duration: 1-2 hours • Avoid bicarbonate if: • Hypocalcemia • Severe lung edema
Glucose and Insulin • Redistribution • RI 10U + D50GW 50cc over 5 min • Consider Albuterol Neb as adjunct • Onset 50-60 min; duration: several hours • Follow F/S
Potassium Removal • Cation-Exchange resin (Kayexalate) • 15-30 gm PO q3-4 hrs or 50 gm in 200 ml retention enema for 30-60 min q4hr • Dialysis: May experience significant hyperkalemia on rebound
Summary • Hyperkalemia • Symptoms? • Diagnosis? • EKG? • Etiology? • Treatment?
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