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WASTE WATER TREATMENT FOR RITONAVIR PRODUCTION PLANT. Presented by Wang Dong Mei July 8, 2000. GENERAL LAYOUT OF PHARMECUTICAL FACTORY. Air Emissions. Sewer Discharge. Laboratory. Hazardous Waste Tank. Direct Discharge. Storm Water. Chemical Process Tanks. Construction. Transportation.
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WASTE WATER TREATMENT FOR RITONAVIR PRODUCTION PLANT Presented by Wang Dong Mei July 8, 2000
GENERAL LAYOUT OF PHARMECUTICAL FACTORY Air Emissions Sewer Discharge Laboratory Hazardous Waste Tank Direct Discharge Storm Water Chemical Process Tanks Construction Transportation Storage
PROBLEM STATEMENT • High concentration of biochemical oxygen demand (BOD): 9,100 mg/l • High concentration of chemical oxygen demand (COD): 85,290 mg/l • High concentration of total organic carbon (TOC): 23980 mg/l • High concentration of total nitrogen (TN): 900 mg/l • High concentration of total solid (TS): 10,480 mg/l
DESIGN OBJECTIVES • Removal of BOD • Removal of COD • Removal of TOC • Removal of TN • Removal of TS
RATIONAL APPROACH • Primary treatment: physical unit operations • Secondary treatment: chemical and biological unit process • Tertiary treatment: combinations of physical, chemical and biological processes
PRIMARY TREATMENT • Screening: to protect pumps, valves, pipelines, and other appurtenances from damage or clogging by rags and large objects • Grit chamber: to remove grit, sand, and gravel, usually following screening • Equalization tank: equalization of flow and loadings, neutralization pH
Equalization & Neutralization Tank Screens Grit Chamber Primary Sediment Tank PRIMARY TREATMENT Influent
SECONDARY TREATMENT • Flocculation and coagulation: to apply chemical mixing to increase the removal of COD • Primary sedimentation: to remove chemical precipitation, settle-able solids, and particular matter • Activated sludge: to remove BOD by microorganism degradation • Secondary sedimentation: to remove settable-able solids
Flocculation and Coagulation Activated Sludge Pond Primary Sedimentation Secondary Sedimentation SECONDARY TREATMENT
TERTIARY TREATMENT Two-step biological nitrification/denitrification: • Removal of nitrogen by using trickling filters • Ammonia is converted aerobically to nitrate(NO3-) (nitrification) in the first step • Nitrates are converted to nitrogen gas (denitrification)
DISINFECTION • Disinfect pathogen or other organisms by applying Cl2 • Chlorate contact tank
SLUDGE PROCESSING • Sludge thickening • Sludge stabilization • Anaerobic sludge digestion • Gas production and collection • Sludge disinfection • Sludge dewatering • Land fill