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zfbiolabs

www.zfbiolabs.com. BioSciencs Foro. November 8th, New York. ZF Biolabs. ZF Biolabs is a spanish biotechnology, established in 2003 and fully devoted to R&D activities in biomedicine and toxicology, working exclusively with zebrafish as the selected model organism.

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zfbiolabs

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  1. www.zfbiolabs.com BioSciencs Foro November 8th, New York

  2. ZF Biolabs ZF Biolabs is a spanish biotechnology, established in 2003 and fully devoted to R&D activities in biomedicine and toxicology, working exclusively with zebrafish as the selected model organism.

  3. Zebrafish use in Biomedical Research

  4. ZF Biolabs R&D • Development of toxicity assays based on the use of the zebrafish embryo (develomental toxicity, neurotoxicity, cardiotoxicity, hepatotoxicity and short term toxicity). • Functional genomics: analysis of genes and phenotypes in zebrafish using morpholino oligonucleotide loss-of-function technique to study human diseases. • Development of new zebrafish supporting technologies aimed to improve the efficiency of embryo production.

  5. ZF BIOLABS COLLABORATIVE RESEARCH PROJECTS • Partner of the EU R&D Project Nuclear envelope-linked rare human diseases: from molecular pathophysiology towards clinical applications” coordinated by the Medical University of Vienna. The role of ZF Biolabs is knocking down Lamin-A gene in zebrafish, screening for functional readouts of pathological phenotypes, identifying molecular drug targets and screening for new drugs. • Partner of the project “Role of FAAH in neuroprotection” in collaboration with Univ. of Salamanca, to develop a transgenic zebrafish model for discovering new neuroprotective drugs. • In collaboration with Canal de Isabel II, the public company in charge of managing the water in the Madrid region, ZF Biolabs is involved in the research project “Development of a new toxicity assay for detecting cyanotoxins in drinkable water using zebrafish embryos”.

  6. ZF Biolabs interest in USA • ZF Biolabs is in contact with some USA Pharmaceutical companies, which are interested in the new toxicity assays and related zebrafish technology. • ZF Biolabs will present its R&D results at the Health and Environmental Sciences Institute (HESI) Workshop on Alternative Assays For Developmental Toxicity, that will be held on February 27-28, 2007, in Cary (North Carolina). • According to the possibility of collaboration with US companies ZF Biolabs will study alliances with established US companies and/or other alternatives.

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