Neonatal Ventilation and Nasal CPAP Market Analysis | Coherent Market Insights

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2. Neonatal Ventilation and Nasal CPAP Market Analysis (2020-2027) • Neonatal ventilation and nasal CPAP are mechanical ventilation, which supports neonates with respiratory distress. Neonatal ventilators use a constant flow of conditioned gas, also known as bias flow, through the breathing circuit to produce positive pressure and nasal continuous positive airway pressure (CPAP) therapy is a nonsurgical treatment that provides a steady flow of air to the lungs through the nose. In the neonatal intensive care unit environment, NCPAP is a relatively simple and effective therapy for respiratory distress syndrome. • According to data published by US National Library of Medicine, in 2014, respiratory distress is one of the most common reasons an infant is admitted to the neonatal intensive care unit, wherein, 29% of late preterm infants are admitted to the neonatal intensive care unit due to respiratory distress and Neonatal Respiratory Disease Syndrome NRDS accounted for 2.3% of all infant deaths in the U.S. in 2013

3. Global Neonatal Ventilation and Nasal CPAP Market- Impact of COVID-19 Analysis • The impact of COVID-19 on the global neonatal ventilation and nasal CPAP market has affected in a positive way. Scarcity of ventilators during this pandemic has been an important issue throughout the world. • The governments of various countries have sanctioned loans for boosting the production and manufacturing of ventilators in health care sectors. Thus, there has been significant changes in healthcare infrastructure, as small cities and towns are incorporating modern facilities to encompass ventilator systems within their hospitals and nursing homes. All these factors are key drivers to boost application of intensive care ventilators in COVID-19 pandemic.

4. Global Neonatal Ventilation and Nasal CPAP Market- Drivers • Neonatal ventilation and nasal CPAP are effective treatment methods for respiratory distress in neonates. There has been sustainable growth in research and development in the global neonatal ventilation and nasal CPAP market from last decade. For instance, in 2016, B&B Medical Technologies announced that the Bubbler 12.5 cm H2O Pressure Relief Manifold is available for immediate sale. The unit is for use in bubble CPAP systems and is a companion product to B&B’s popular Bubbler Water Seal CPAP Valve. The Pressure Relief Manifold is U.S. Food and Drug Administration (FDA) approved and carries the CE mark. • According to data published by US National Library of Medicine in 2014, around 1% of infants develop respiratory distress syndrome globally and in the U.S., 12% of babies were born prematurely having risk of respiratory distress and accounted for 2.3% of infant deaths due to respiratory distress syndrome in 2013. Such factors are expected to drive the global neonatal ventilation and nasal CPAP market growth over the forecast period.

5. Global Neonatal Ventilation and Nasal CPAP Market- Restraints • Discomfort of patients while using CPAP in nasal cavity and claustrophobia is main restraint for neonatal ventilation and nasal CPAP. However, other restraints commonly observed are leaks, added death space, weight long trigger, probe cost, and invasive. • In India, neonatal and nasal CPAP are out of pocket expense for most of the Indian population. For instance, according to India Mart, the cost of neonatal ventilator is approx. US$ 7,680 per unit in India. These factors are expected to restrain the global neonatal ventilation and nasal CPAP market growth over the forecast period.

6. Global Neonatal Ventilation and Nasal CPAP Market- Regional analysis • On the basis of region, the global neonatal ventilation and nasal CPAP market is segmented into North America, Latin America, Europe, Asia Pacific, Middle East, and Africa. In North America, according to journal published by US National Library of Medicine in 2019, 12% of babies born in the U.S. were born prematurely–a higher rate than in other developed countries and Neonatal Respiratory Disease Syndrome (NRDS) accounted for 2.3% of all infant deaths in the U.S. in 2013. Product launches in the region are supporting growth of the market. • For instance, in 2019, ResMed (US) launched AirFit N30i, its first top-of-head-connected nasal CPAP mask, across the U.S. Moreover, in 2018, Vyaire Medical acquired Acutronic and IMTmedical. Both the new acquisitions are based in Europe, with Acutronic split between Switzerland and Germany and IMTmedical based solely in Switzerland and Chicago. Key players in this region are Acutronic Medical Systems AG, Löwenstein Medical GmbH & Co. KG Niederlassung.

7. s • Moreover product launches in the Asia Pacific region are supporting growth of the market. For instance, in 2019, InnAccel Technologies Pvt Ltd. (India) launched SAANS: portable neonatal CPAP device for infants with respiratory distress syndrome. These factors are expected to support growth of the market over the forecast period.

8. Global Neonatal Ventilation and Nasal CPAP Market - Competitive Landscape • Key players operating in global neonatal ventilation and nasal CPAP market include ResMed INC, Airon Corporation, GE Healthcare, Respironics, Inc, Acutronic Medical Systems AG, Lowenstein Medical GmbH & Co. KG Niederlassung, InnAccel Technologies Pvt Ltd, Phoenix Medical Systems Pvt. Ltd, PT. Fyrom International, BMC Medical Co., Ltd, Fisher & Paykel Healthcare Corporation Limited, Somnomed Ltd, Oventus Medical, Braebon Medical Corporation, and Drägerwerk AG.

9. Key Developments- • At Arab Health 2020, Dräger launched the new Evita V600 and V800 ventilators designed to support daily clinical tasks in the ICU. Both ventilators combine high performance ventilation with an aesthetic design, enabling quick and efficient operation from the first onset of lung protective ventilation until the integration of a patient care-centered intensive care workplace. • In 2019, Silver Cross Hospital in New Lenox, US, planned to add a US$ 12.8 million neonatal intensive care unit • In 2019, Vyaire Medical received the U.S. FDA clearance for Bellavista 1000e ventilator system. The Bellavista 1000e ventilator’s approval includes support for neonatal to adult patients, More than 8,200 Bellavista 1000e ventilators of Vyaire are in use across 92 countries outside the U.S.

10. Global Neonatal Ventilation and Nasal CPAP Market- Taxonomy • By Product Type • Invasive Ventilation • Non-invasive Ventilation • By End User • Hospitals • Clinics • Ambulatory Surgical Centers • Home Care Setting

11. By Mobility • Intensive Care Ventilators • Portable/Transportable Ventilators • By Technology • Mechanical Ventilators • High Frequency Ventilators • Volume Targeted Ventilators • Hybrid Ventilators • By Mode • Pressure Mode Ventilation • Combined Mode Ventilation • Volume Mode Ventilation

12. By Region • North America • Latin America • Europe • Asia Pacific • Middle East • Africa

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