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Training

Training. Essential nutrients for your health. c alcium active Denk 02.2015. Content. Calcium active Denk Product Information Key Selling Points Posology & Ingredients Target Group Role of Calcium Osteoporosis Calcium Deficiency Special Cosiderations Dietary Sources

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Training

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  1. Training Essential nutrients for your health calcium active Denk 02.2015

  2. Content Calcium active Denk Product Information Key Selling Points Posology & Ingredients Target Group Roleof Calcium Osteoporosis Calcium Deficiency Special Cosiderations DietarySources Further Tips GoodtoKnow Hypercalcemia Other Denk Nutrition Products Train the Brain – Quiz References

  3. 1. Calcium active Denk

  4. 2. Key Selling Points • Verygoodcompliance – only 1 effervescenttablet per day • Easy consumptionwithoutswallowingtablets → ideal forchildren/adolescents • Fruity orange flavour • Beneficialtothemaintenanceofbones, teethandcontributesto a normal musclefunction • Lactosefree • Glutenfree

  5. 3. Posology & Ingredients • INTAKE • The recommendedintakeis1 effervescenttablet per daytakenwith a meal • If a higherdossageisnecessary, therecommendedintakeis1 effervescenttablet in themorningand 1 in theevening(→ higherabsorption) • Easy consumption INGREDIENTS * Calcium= Calciumcarbonate

  6. 4. Target Group FAST CALCIUM SUPPLY FOR Sport Growth phase Pregnancy & Breastfeeding Lack of calcium intake through nutrition / medication Postmenopausal women Elderly people e.g. in case of lactose intolerance or diets, proton-pump inhibitors, diuretics etc. higher need for calcium, esp for osteoporosis prophylaxis

  7. Train theBrain What is the target group for Calcium active Denk? • Pregnant and breastfeeding women • Postmenopausal women (> 40 years) who are at risk of osteoporosis (prophylaxis treatment) • Elderly people • Special nutrition habits (high consume of alcohol, beverages, caffeine, tea, lactose intolerant people, vegetarians) • Children and adolescents (growth phase) in case of medical advice • Extremely physically active people • Intake of specific medications (proton pump inhibitors, diuretics, corticosteroids etc. )

  8. 5. Calcium • Roleofcalcium • Approximately99% ofthebody‘scalciumisstored in thebonesandteeth • The other1% isfoundin bloodandhasotherimportantuses, e.g. musclecontraction, maintenanceoftheheartbeatorneurotransmitterrelease • Boneitselfundergoescontinuousremodeling, withconstantresorptionanddispositionofcalciumintonewbone • The balancebetweenboneresorptionanddepositionchangeswithage • → osteoporosiscandevelop Osteoblasts: creatingbone Osteoclasts: destroyingbone Video

  9. 6. Osteoporosis • Whatisosteoporosis? • Disordercharacterizidedbyporousandfragile bones • The lossofbonesoccurssilentlyandprogressively • Most associatedwithfracturesofthe hip, vertebrae, wrist, pelvis, ribsandotherbones • Factorsthatincreasetheriscofdevelopingosteoporosis: • Femalesex (esp. in postmenopausal women due todecreasedamountsofestrogen → boneresorption↑, calciumabsorption↓ ) • Advancedage (in bothmenandwomen) • Thin, inactivewomen • Smoking cigarettes • Excessiveamountsofalcohol • Family historyofosteoporosis • In men, a decrease in testosteronelevelshascomparable (but lesspronounced) effect • Some medications1 Take Calcium active Denk asosteoporosisprophylaxis

  10. 7. Calcium Deficiency • Calcium Deficiency • Inadequateintakesofdietarycalciumproducenoobvioussymptoms • Hypocalcemiaresults e.g. fromuseofcertainmedications • Symptoms ofhypocalcemia: • Numbness • Tingling in thefingersandtoes • Musclecramps (in legsorarms) • Convulsions • Lethargy • Poor appetite • Abnormal heartrhythms

  11. 8. Special Considerations • Lactoseintoleranceorcow‘s milk allergy • More than75% ofthepopulationworldwideislactose intolerant (5% in Northern Europe, > 90% in some African and Asian countries)3 • Lactose-intolerant individualsare at riskofcalciuminadequacyiftheyavoiddairyproducts • Cow‘s milk allergyisaffecting 0.6% - 0.9% ofthepopulation → higherriskofinsufficientcalciumintakebecausepeoplewithcow‘s milk allergyareunabletoconsumeanydairyproducts • Pregnancy & Breastfeeding • Fetal calciumrequirementreachesitsmaximumduringthe 3rd trimester • Recommended DietaryAllowancesforpregnantandbreastfeedingwomenare1300 mg/day(14 – 18 years) or1000 mg/day(19 – 50 years)1, 2

  12. 8. Special Considerations • Growth phase • Especially in periodsofgrowth in childrenandadolescentscalciumisrequiredtobuildbonesandteeth • Upto 90% ofpeakbonemassisacquiredbyage 18 in girlsandbyage 20 in boys • Additional calciumcanbegiven in caseofmedicaladvice • Vegetarians • Vegetariansare at riskofconsuminglesscalciumthan non-vegetariansbecausetheyconsumemore plant productscontainingoxalicandphyticacid→ calciumispoorlyabsorbedbecauseoftheacids • Postmenopausal andamenorrheicwomen • Menopause andamenorrhea (thecondition in which menstrual periodsstop) leadstoreducedcirculatingestrogenlevelsandthereforedecreasedcalciumabsorption

  13. 8. Special Considerations • People withprovenor high riskofdevelopingcalciumdeficiency • Low calciumdiets • High consumeofalcoholicbeverages, caffeine, tea • Intakeofspecificmedications • Steroids • Barbiturates • Phenytoin • L-Thyroxine • Hypogonadisminducing drugs (aromatase inhibitors, methotrexate) • Long-term use of anticoagulants • Proton-pump inhibitors • Thiazolidinediones(diabetes) • Chronic lithium therapy

  14. 9. DietarySources • Dairyproducts • Cheese, milk, yogurt, kefir • Seeds • Poppy, sesame, almonds, hazelnuts Calcium- richfood • Vegetables • Broccoli, greencabbage, parsley, rocket, kale • Fruits • Figs, bananas, calcium-fortified orange juice

  15. 10. Further Tips Makesuretospendminimum half an hour outside duringsunlight → theskinproduces Vitamin D whenexposedtosunlightwhichimprovescalciumabsorption Avoidtoomuchalcohol, caffeine* andtea • Tips • toincreaseyour • calciumintake! Dietary Mg intake increases Ca absorption Well-balanceddiet *moderate caffeineconsumption (1-2 cupsofcoffee) in youngwomenhasno negative effects on bone1

  16. 10. Further Tips • Other Waysto Keep Your Bones Strong andHealthy • Weight-bearingexercises, e.g. liftingweights, walking, climbingstairs, dancing → muslcesgetstrongerwhichhelpsprevents falls andworkingmusclestimulatesboneintobecomingstronger • Staywithinyourdailycalorieneedstomaintain a healthyweight

  17. Train theBrain Which medication leads to a lower calcium level? • Steroids • Barbiturates • Phenytoin • L-Thyroxine • Hypogonadism inducing drugs (aromatase inhibitors, methotrexate) • Long-term use of anticoagulants • Proton-pump inhibitors • Thiazolidinediones (diabetes) • Chronic lithium therapy

  18. 11. GoodtoKnow • Are thereanyspecialconsiderationsifothersupplementsormedicationsaretaken? • Calcium shouldbetaken at least 2 hoursbeforeor after thefollowingmedications: • Iron supplement (e.g. ferro vital+ Denk) • Levothyroxine • Alendronate, risedronateoranotheroneofthebiphosphonatedrugs • Certainantibiotics such astetracyclinesorquinolones

  19. Train theBrain Name some calcium-rich foods! • Dairyproducts • Cheese, milk, yogurt, kefir • Seeds • Poppy, sesame, almonds, hazelnuts • Vegetables • Broccoli, greencabbage, parsley, rocket, kale • Fruits • Figs, bananas, calcium-fortified orange juice

  20. 12. Hypercalcemia • Healthrisksfrom hypercalcemia2 • (Increasedriskof) kidneystones • Renal insufficiency • Vascularand soft tissuecalcification • Hypercalciuria (high levelsofcalcium in theurine) • Tolerable upperintakelevelsfor calcium1:

  21. Train theBrain Explain at least 4 benefits of Calcium active Denk! • Very good compliance – only 1 effervescent tablet per day • Easy consumption without swallowing tablets → ideal for children/adolescents • Fruity orange flavour • Beneficial to the maintenance of bones, teeth and contributes to a normal muscle function • Lactosefree • Glutenfree

  22. 14. Other Denk Nutrition Products FOR FATHERS -TO-BE may change your (family) life FOR MOTHERS -TO-BE

  23. 14. Other Denk Nutrition Products FAST IRON SUPPLY FAST MAGNESIUM SUPPLY FOR MUSCLES, HEART AND NERVES

  24. 15. Train theBrain • What is the target group of calcium active Denk? • Which medication leads to a lower calcium level? • Name some calcium-rich foods • Explain at least 4 benefits of Calcium active Denk!

  25. 15. Train theBrain • 1) • Pregnant and breastfeeding women • Postmenopausal women (> 40 years) who are at risk of osteoporosis (prophylaxis treatment) • Elderly people • Special nutrition habits (high consume of alcohol, beverages, caffeine, tea, lactose intolerant people) • Children and Adolescents (growth phase) in case of medical advice • Extremely physically active people • Intake of specific medications (proton pump inhibitors, diuretics, corticosteroids etc. • 2) • Numbness • Tingling in the fingers and toes • Muscle cramps (in legs or arms) • Convulsions • Lethargy • Poor appetite • Abnormal heart rhythms • 3) • Very good compliance – only 1 effervescent tablet per day • Easy consumption without swallowing tablets → ideal for children/adolescents • Fruity orange flavour • Beneficial to the maintenance of bones, teeth and contributes to a normal muscle function • Lactosefree • Glutenfree

  26. 15. Train the Brain • 4) • Dairyproducts • Cheese, milk, yogurt, kefir • Seeds • Poppy, sesame, almonds, hazelnuts • Vegetables • Broccoli, greencabbage, parsley, rocket, kale • Fruits • Figs, bananas, calcium-fortified orange juice • 5) • Steroids • Barbiturates • Phenytoin • L-Thyroxine • Hypogonadism inducing drugs (aromatase inhibitors, methotrexate) • Long-term use of anticoagulants • Proton-pump inhibitors • Thiazolidinediones (diabetes) • Chronic lithium therapy

  27. 16. References • National Institutes ofHealth, Office ofDietary Supplements, Dietary Supplement Fact Sheet: Calcium • www.orthopaedicsone.com • Medication: Steroids, barbiturates, phenytoin, L-Thyroxine, hypogonadism inducing drugs (aromatase inhibitors, methotrexate), long-term use of anticoagulants, proton-pump inhibitors, Thiazolidinediones (diabetes), chronic lithium therapy • New Reference Values for Calcium, German Nutrition Society, 2013 • A.C. Bulhões, H.A.S. Goldani, F.S. Oliveira, U.S. Matte, R.B. Mazzuca1 and T.R. Silveira (2007). "Correlationbetweenlactoseabsorptionandthe C/T-13910 and G/A-22018 mutationsofthelactase-phlorizinhydrolase (LCT) gene in adult-type hypolactasia". Brazilian Journal of Medical and Biological Research 40 (11): 1441–1446. • Massey LK, Whiting SJ., Caffeine, urinary calcium, calcium metabolism and bone, J Nutr. 1993 Sep;123(9):1611-4. • Food and Nutrition Board, Institute ofMedicine, National Academies, Tolerable UpperIntake Levels

  28. Join Denk Pharma! Our contributions to keeping you* healthy: • affordable pharmaceuticals for your therapy • German high premium quality for tablets, sachets, • packaging, studies, consultation, availability, support, etc… • raise awareness by conducting Check Up Days (blood glucose, • blood pressure, cholesterol and triglyceride) • constantly enhancing the product portfolio *patients, doctors, pharmacists, sales reps

  29. HEALTHCARE MADE IN GERMANY since 1948

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