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Maurizio De Luca MD Department of Surgery – Regional Hospital of Vicenza – Italy

XXI Congresso Nazionale SICOb. Mini Gastric Bypass: l ’ opinione degli esperti La gestione delle complicanze. Esperienza personale e letteratura a confronto. Maurizio De Luca MD Department of Surgery – Regional Hospital of Vicenza – Italy. Cagliari, 25-27 Aprile 2013.

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Maurizio De Luca MD Department of Surgery – Regional Hospital of Vicenza – Italy

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  1. XXI Congresso Nazionale SICOb Mini Gastric Bypass: l’opinione degli esperti La gestione delle complicanze. Esperienza personale e letteratura a confronto Maurizio De Luca MD Department of Surgery – Regional Hospital of Vicenza – Italy Cagliari, 25-27 Aprile 2013

  2. Results of Mini Gastric Bypass – Vicenza Padova Background • Our Series before Mini Gastric Bypass • Our Primary Surgery • Sept 1993 Dec 2012 : Gastric Banding → 2400 Patients • 0 moratility • 5.4% complication requiring reoperation • Mean %EWL 49% at 12 years • 25% of GB with %EWL < 30 (failure) APPROPRIATE BARIATRIC OPERATION – POSSIBLE ROLE OF STAGED SURGERY M DE LUCA, G Segato, L Busetto, D Asthon, F Favretti. Obesity Surgery, 18, 4, 153, 471-472, 2008 Maurizio De Luca

  3. Results of Mini Gastric Bypass – Vicenza Padova Background • Our Series before Mini Gastric Bypass • Our Remedial Surgery from Dec 1995 to January 2011 • Duodenal Switch (DS) → 155 Patients (F/M 98/57) • open/VLS 41/114 VLS from Jan 2001 • 0,7% mortality (1 case for malignant hypertermia) • 16.7% post-op surgical complication (fistula, bleeding, internal hernia) • 5.5% post-op medical complication (non fatal PE, pneumoniae, ARDS, MI) • 3% surgical revisions (diarrhea, low protein,excess WL, poor WL) • 12.5% metabolic complication requiring rehospitalization • arthralgia, peripheral edema, vomiting, diarrhea, nutrients deficiences • 39% of patients proctitis, alitosis, acid sweating • 75% EWL 13 years follow up • Comorbidities resolution 94% hyperlipemia, 91% Type II Diabetes ADJUSTABLE GASTRIC BANDING WITH DUODENAL SWITCH (BANDINARO): SEQUENTIALTREATMENT IN A FAILED RESTRICTIVE PROCEDURE (LAPAROSCOPIC PRELIMINARY EXPERIENCE) DE LUCA M, Segato G, Busetto L, Ceoloni A, Banzato O, Enzi G, Favretti F Obesity Surgery, 16,4,2006, 400. Maurizio De Luca

  4. Resultsof Mini Gastric Bypass • Mini Gastric Bypass : Vicenza Hospital /Padova University Series • Antrophometric Data • April 2011 – December 2012 (20 months experience) • 42 Patients (F/M 26/16) • Primary Surgery /Remedial Surgery for Band Failure 4/38 • Age 39.7 ± 10 (19-62) • Weight kg 138.7 ± 26.8 (93-182) • BMI 45.6 ± 8.1 (35-61) • Lap/Open 42/0 • Skin-to Skin Time 110 ± 4.65 (85-190) No published data Maurizio De Luca

  5. Resultsof Mini Gastric Bypass - Technical Details • Performed by Laparoscopy (4-5 Trocar) • 20-30 ml Gastric pouch (vertical gastrectomy) • Gastro-jejunal anastomosis with a stoma diameter of 1.5-2 cm • L-L anastomosis • Antireflux Stitches • Omega Loop 220 cm • Antecolicanastomosis One Anastomosis Gastric Bypass: a simple, safe and efficient surgical procedure for treating morbid obesity M Garcia Caballero and M Carbajo NutricionHospitalaria, XIX, (6) 372-375, 2004 Maurizio De Luca

  6. Resultsof Mini Gastric Bypass asRemedialSurgery Weight Loss (38 Pts) Kg months Maurizio De Luca

  7. Resultsof Mini Gastric Bypass asRemedialSurgery Weight Loss (38 Pts) % EWL months Maurizio De Luca

  8. Resultsof Mini Gastric Bypass (42 Pts) • Comorbidities • Diabetes • 12 obese Pts DM2 • 3 years, • HgA1c > 7.5% • Failure previous medical treatment • Mean Follow-up: 13 .1months (±2.3) • Dyslipidemia • 11 obese Pts with hypercolesterolemia and/or hypertrygliceridemia • Mean Follow-up: 12.4months (±1.9) Complete Remission: 9 pts (75%) Improvement: 12 pts (100%) Complete remission 10 pts (90.1%) Maurizio De Luca

  9. Resultsof Mini Gastric Bypass (42 Pts) Comorbidities Maurizio De Luca

  10. Results of Mini Gastric Bypass – Vicenza Padova Series • Nutritional Deficiences • Iron • Calcium • Zinc • VitaminD • Vitamin A • Vitamin K • Protein Dolen K et al. A clinical and nutritional comparison of biliopancreatic diversion with and without duodenal switch. Ann Surg 2004; 240-51 Slater GH, Serum fat-soluble vitamin deficiency and abnormal calcium metabolism after malabsorptive bariatric surgery. J Gastrointestinal Surg 2004; 8: 48-65 APPROPRIATE BARIATRIC OPERATION – POSSIBLE ROLE OF STAGED SURGERY M DE LUCA, G Segato, L Busetto, D Asthon, F Favretti. Obesity Surgery, 18, 4, 153, 471-472, 2008 Maurizio De Luca

  11. Results of Mini Gastric Bypass – Vicenza /Padova Series Complication of MGB Primary MGB 4 Pts Revisional 38 Pts • Short Term Complications • Leakage 0 4.7% • Omega loop • Bleeding 0 2.3% • abdominal, intraluminal, thoracic • Major atelectasis 0 0 • Deep vein thrombosis 0 0 • Death 0 0 • Long Term Complications (0 redo) • Stomal Ulcer 0 0 • Bile Reflux 0 2.3% • Excessive Weight Loss (malnutrition) 2.3% 0 • Bowel obstruction 0 0 • Total Redo Surgery (1 Pts 1° day post-op) 2.3% Not published data Maurizio De Luca

  12. Results of Mini Gastric Bypass – Vicenza /Padova Series Side Effects of MGB Primary MGB 4 Pts Revisional 38 Pts • Asthenia 0 7.7% <0.001 • Diarrhea 2.3% 2.3% <0.001 • Bloating 0 4.7% <0.01 • Epigastralgia 2.3% 4.7% <0.05 • Vomiting 0 2.3% <0.01 • Major metabolic consequences 0 0 Not published data Maurizio De Luca

  13. Resultsof Mini Gastric Bypass - Literature Complication of MGB Primary MGB 923 Pts Revisional 77 Pts • Short Term Complications (6 redo) 2.7% 11% <0.001 • Leakage 0.4% 3.8% <0.001 • Gastrojejunostomy, gastric tube, gastric remnant • Bleeding 1.6% 6.4% <0.68 • abdominal, intraluminal, thoracic • Major atelectasis 0.21% 1.29% <0.09 • Deep vein thrombosis 0.1% 0% <0.77 • Death 0 0 • Long Term Complications (7 redo) 0.69% 5.2% <0.03 • Stomal Ulcer 0.65% 0 <0.102 • Bile Reflux 0 5.2% <0.001 • Excessive Weight Loss (malnutrition) 0,4% 0 <0.001 • Bowel obstruction 0 0 <0.562 ONE THOUSANDS CONSECUTIVE MINI-GASTRIC BYPASS. SHORT AND LONG TERM OUTCOME Noun R, Skaff J, Riachi E Obesity Surg, 22, 697-703, 2012 Maurizio De Luca

  14. Results of Mini Gastric Bypass - Literature Complication of MGB Primary/Revisional MGB 1126 Pts • Short Term Complications 1.4% • Leakage 0.9% • Gastrojejunostomy, gastric tube, gastric remnant • Bleeding 0.3% • abdominal, intraluminal, thoracic • Gastric Perforation 0.1% • Death 0.1% • 1 pulmonary thromboembolism/ 1 gastric wall necrosis • Long Term Complications 0.8% • Stomal Ulcer 0.4% • Gastrojejunalstenosis 0.4% • Total Redo Surgery 1.3% BYPASS GASTRICO LAPAROSCOPICO DE UNA SOLA ANASTOMOSIS (BAGUA) ASISTIDOCON BRAZO ROBOTICO: TECNICA Y RESULTATOS EN 1126 PACIENTES Caballero MAC, De Solorzano JO, Garcia-Lanza C CirurgiaEndoscopica, 9,1, 6-13, 2008 Maurizio De Luca

  15. Maurizio De Luca

  16. Lee GBP vs MGP: 10 year results - Complication Lee WJ et al. Laparoscopic Roux en Y Gastric Bypass vs Mini Gastric Bypass for the treatment of Morbid Obesity: a 10 Years experience Obesity Surgery 22: 1827-1834, 2012 Maurizio De Luca

  17. Lee GBP vs MGP: 10 year results Weight Loss Lee WJ et al. Laparoscopic Roux en Y Gastric Bypass vs Mini Gastric Bypass for the treatment of Morbid Obesity: a 10 Years experience Obesity Surgery 22: 1827-1834, 2012 Maurizio De Luca

  18. Lee GBP vs MGP: 10 year results Lee WJ et al. Laparoscopic Roux en Y Gastric Bypass vs Mini Gastric Bypass for the treatment of Morbid Obesity: a 10 Years experience Obesity Surgery 22: 1827-1834, 2012 Maurizio De Luca

  19. Results of Mini Gastric Bypass – Conclusion 1 • Less Surgery compared to GBP and BPD • Quicker Surgery compared to GBP and BPD • Low peri-operative complications compared to GBP and BPD • Long Term Weight Loss as BPD (75% EWL at 10 yrs) • Remission /improvement of Diabetes in 85-90 % of cases • Remission of hyperlipidemia in 85-95% of cases • Absence of some BPD side effects (like diarrhea, hemorrhoids, proctitis etc.) • Reduction of metabolic consequences of BPD (protein malnutrition) Maurizio De Luca

  20. Results of Mini Gastric Bypass – Conclusion 2 • In our series first choice operation is Gastric Banding (72% of Pts) • First option for Bile Reflux Obese Pts is GBP • First option for Diabetic or Hyperlipemic Obese Pts is MGB • First option as remedial surgery is MGB • Current studiies show that MGB is an effective, low-risk and low-failure bariatric procedure • MGB can be revised in GBPor reversed if necessary Maurizio De Luca

  21. Resultsof Mini Gastric Bypass Thank You for your attention Maurizio De Luca

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