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B rain imaging research

Explore the features of different brain imaging methods such as PET, fMRI, EEG, and MEG. Understand their spatial and temporal resolutions and their applications in researching schizophrenia and event-related potentials (ERPs).

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B rain imaging research

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  1. Brain imaging research

  2. Features of all methods PET excellent spatial resolution fMRI poor temporal resolution EEG poor spatial resolution MEG excellent temporal resolution

  3. Features of all methods Meyer-Lindernberg, A. From maps to mechanisms through neuroimaging of schizophrenia. Nature, 468: 194-202

  4. Basic introduction to ERPs ERP … event-related potential result of processed raw EEG signal (electroencephalography) The event represents a controlled independent variable The potential represents the measured dependent variable tone odour taste WORD tactile stimulus

  5. An actual ERP

  6. 0ms 0ms 0ms 0ms

  7. Rohes Signal gefiltert Gemitteltes Signal gefiltert 0ms 0ms 1000ms 1000ms

  8. Gemittelte Signale gefiltert 1000ms 0ms

  9. Basic EEG introduction EEG measures voltage fluctuations resulting from ionic current flows within the neurons of the brain Hans Berger • first human EEG in 1924 • invented the electroencephalogram Brain potentials from his 16 year old son Klaus

  10. More history 1934/35: Confirmation by the labs of Adrian, Jasper, and Davis 1939: Single-trial ERPs reported by Pauline & Hallowell Davis 1940-1960: Sensory ERPs recorded with primitive methods 1962: First publication of computer-averaged ERPs by Galambos

  11. Basics of Neurophysiology(where does an EEG signal come from?) Magnification for microscopic vision

  12. Basics of Neurophysiology(where does an EEG signal come from?)

  13. Different faces of EEG

  14. Other methods to record brain activity Positron Emission Tomography (PET) Functional Magnet Resonance Imaging (fMRI) Magnetoencephalography (MEG)

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