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Repetition Suppression Study of non-Mirroring Mirror Neurons

Repetition Suppression Study of non-Mirroring Mirror Neurons. Geoff Bird, Hannah Widmann , Clare Press, Caroline Catmur , James Kilner , Celia Heyes. Mirror Neurons and RS. Pairs of Action Stimuli – Obs/Exe and Exe/Obs Cross modal RS for repeat vs non-repeat trials.

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Repetition Suppression Study of non-Mirroring Mirror Neurons

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  1. Repetition Suppression Study of non-Mirroring Mirror Neurons Geoff Bird, Hannah Widmann, Clare Press, Caroline Catmur, James Kilner, Celia Heyes

  2. Mirror Neurons and RS • Pairs of Action Stimuli – Obs/Exe and Exe/Obs • Cross modal RS for repeat vs non-repeat trials. • 96 repetitions, 43mins, 10Ss, 16 slices on IFG. Kilner et al 2009, JoN

  3. Alternative RS Design • Unimodal (exe) study of action planning. • 19 Ss, 4sec action execution event, 4sec rest. 36 trials (~5min) in total. Hamilton & Grafton 2008, HBM Non-Mirroring MNs & RS SESSION 3 SESSION 1 SESSION 2 TRAINING Repeat Non-Repeat

  4. Design 2 (Suppression: Long vs Short) x 2 (Repeat vs Novel) x 2 (ObsExe vs ExeObs) Aobs (250ms) Bexe (Jit 2secs) Bobs (250ms) Aexe (Jit 2 secs) Aexe (250ms) Bobs etc 8 conditions x 32 reps per cell = 256 trials x (1125ms mean gap duration + 750ms stim duration) = 8min 3 sessions = 24mins + 15mins = 39mins per subject (45mins) 45mins * 20subjects = 15hrs scanning time. Analysis – Full-Factorial ANOVA using SPM8. Contrast repeat vs non-repeat trials after long and short delays. Check to see whether obs/exe or exe/obs makes a difference. 32-channel head coil. Potentially reduce coverage for faster scanning (IFG?) Custom-built response apparatus – borrowed from James Kilner. 2secs

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