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Kwashiorkor. Syeda Fatma H. Bukhari. What is Kwashiorkor?. Kwashiorkor is an acute form of childhood protein-energy malnutrition The name is derived from the Ga language of coastal Ghana, translated as “the sickness the baby gets when the new baby comes” or “the sickness of the weaning”
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Kwashiorkor Syeda Fatma H. Bukhari
What is Kwashiorkor? • Kwashiorkor is an acute form of childhood protein-energy malnutrition • The name is derived from the Ga language of coastal Ghana, translated as “the sickness the baby gets when the new baby comes” or “the sickness of the weaning” • Alternative names are • Protein malnutrition • Protein-calorie malnutrition • Malignant malnutrition
Causes This disease is more common in very poor countries. It often occurs during a drought or other natural disaster, or during political unrest. These conditions are responsible for a lack of food, which leads to malnutrition. Food supply can also be limited due to natural disasters, political unrest, poverty etc. • Low protein diet • Famine • Limited food supply • Lack of education • Weaning of child from breast milk
Signs & Symptoms • Changes in skin pigment and flaky skin • Hair changes (change in color or texture) • Decreased muscle mass • Large belly that sticks out (protrudes) • Diarrhea • Failure to gain weight and grow • Fatigue • Irritability • Lethargy or apathy • Rash (dermatitis) • Shock (late stage) • Swelling (edema) • Increased and more severe infections due to damaged immune system
Possible Complications • Permanent mental and physical disability • Shock • Coma • Death
Diagnosis The creatinine clearance test compares the level of creatinine in urine with the creatinine level in the blood. (Creatinine is a breakdown product of creatine, which is an important part of muscle.) The test helps provide information on kidney function. • The physical examination may show an enlarged liver (hepatomegaly) and general swelling. • Tests may include: • Arterial blood gas • BUN • Complete blood count (CBC) • Creatinine clearance • Serum creatinine • Serum potassium • Total protein levels • Urinalysis
Treatment • Immediate restoration of blood volume and maintenance of blood pressure • Getting more calories and protein • SLOW reintroduction of food • Vitamin and mineral supplements • Lactase enzyme