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CROHN’s DISEASE. STJEPAN ĆURIĆ Mentor: A. Žmegač Horvat. Dr. Burrill Bernard Crohn . in 1932 he described a series of patients with inflammation of the terminal ileum , the area most commonly affected by the illness. What is Crohn’s?.
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CROHN’s DISEASE STJEPAN ĆURIĆ Mentor: A. Žmegač Horvat
Dr. Burrill Bernard Crohn • in 1932 he described a series of patients with inflammation of the terminal ileum, the area most commonly affected by the illness
What is Crohn’s? • inflammatory disease of the intestines that may affect any part of the gastrointestinaltract from mouth to anus
Symptoms • abdominalpain • diarrhea (which may be bloody) • vomiting • weight loss • skin rashes • arthritis • inflammation of the eye
Causes • genetics (mutationsin CARD15) • environmentalfactors • immunesystem • microbes (Mycobacteriumaviumsubspeciesparatuberculosis)
Diagnosis • endoscopy • radiologictests • bloodtests • comparisonwithulcerativecolitis
Treatment • medication (corticosteroids, 5-aminosalicyilic acid, azathioprine, mercaptopurine, methotrexate, infliximab) • lifestyle changes (hydration) • surgery
References: • MayoClinic: Crohn's Disease • National Digestive Diseases Information Clearinghouse