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Plab bedside. Qumber. qumber: Bed side. HPI. When did it start What was the first thing noticed Progress since then Ever had it before. qumber: Bed side. hands. 5.Warm sweaty hands Hyperthyroidism 6.Cold moist hands Anxiety 7.Cold dry hands hypothyroidism. qumber: Bed side.
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Plab bedside Qumber
qumber: Bed side HPI • When did it start • What was the first thing noticed • Progress since then • Ever had it before
qumber: Bed side hands • 5.Warm sweaty hands • Hyperthyroidism • 6.Cold moist hands • Anxiety • 7.Cold dry hands • hypothyroidism
qumber: Bed side • 8.Pallor of palmer crease • Anemia • 9.Palmer erythema • Cirrhosis pregnancy polycythemia • 10.Pigmentation of creases • Normal in Asian/blacks Addison
qumber: Bed side • 11.Fibrosis and contracture of palmer fascia • Dupuytrens contracture • Liver disease trauma epilepsy aging • 12.Swollen PIP joints with DIP joint sparing • RA • 13.Swollen DIP joints • Osteoarthritis gout psoriasis
qumber: Bed side • 14.Distal and proximal nodes • Heberden’s and Bouchard’s nodes • Osteoarthritis
15.Spoon shape (koilonychias) .Iron deficiency syphilis IHD 16.Destruction of nails (onycholysis) Hyperthyroidism fungal infection psoriasis 17.Transverse furrows Beaus lines (temporary growth arrest due to severe illness) Nail growth rate=0.1mm/day,measure stress date from cuticle qumber: Bed side Nails
qumber: Bed side • 18.Transverse bands white and parallel • Mees lines Hypoalbuminaemia • 19.Pink/brown band on nail tip • Terry's lines- • cirrhosis CCF DM cancer aging
qumber: Bed side • 20.Fine longitudinal streaks under nail • Splinter hemorrhages-Infective endocarditis • 21.Pitting • Psoriasis Alopecia Areata
qumber: Bed side • 22.Nail fold infarcts • Vasculitic disorders • 13.Painful swollen nail with intermittent discharge • Chronic paronychia- chronic infection of nail fold • Rx. Dry erythro250mg/6hrPO Nystatin oint.
qumber: Bed side clubbing 1.Thoracic causes • 24.Bronchogenic CA(not small cell) • 25.Chronic lung supporation • Empyma • abscess • Bronchiactesis • Cystic fibrosis • 26.Fibrosing Alveolitis • 27.mesothelioma
qumber: Bed side 2.GI causes • 28.Inflammatory bowl disease • 29.cirrohsis • 30.Malabsorption • 31.Lymphoma
qumber: Bed side 3.Cardiac causes • 32.Cyanotic congenital heart disease • 33.endocarditis • 34.Atrial myxoma
qumber: Bed side 4.Rare causes of clubbing; • 35.Familial • 36.Thyroid acropachy 5.Unilateral clubbing bc of • 37.Axillary artery aneurysm • 38.Brachial A-V malformation
Abdominal distension • 39.fat • 40.faeces • 41.fluid ( shifting dullness, fluid thrill) • 42.fetus • 43.flatus ( air is resonant on percussion) • 44.food(malabsorption)
AD due to Air • 45.GI obstruction (inc. faeces) || • 46. Aerophagy (air swollowing ) V
AD due to ascites • 47. malignancy* • 48. Hypoproteinaemia (nephrotic ) • 49. Right heart failure • 50. Portal hypertension qumber: any organ e.g liver, pancrease, kidney stomach colon*
qumber: AD due to solids • 51.Malignancy* • 52.Lymph nodes • 53.Aorta aneurysm • 54.Cysts • renal • pancrease qumber: any organ e.g liver, pancrease, kidney stomach colon*
AD due to pelvic masses • 55. Bladder • Full • CA • 56. Fibroid, fetus • 57. Ovarian ( cyst, cancer) • 58. Uterine cancer qumber:u cant get below pelvic masses
Right illiac fossa mass • 59.appendix ( mass, abscess) • 60.kidney mass • 61.Caecum CA • 62.Crohns or TB mass • 63.Intussusceptions • 64.Amoebic mass • 65.Any of pelvic mass mentioned above
hepatomegaly • 66.Right heart failure • 67. Pulsatile hepatomegaly • Tricuspid incompetence • 68.Infections • Glandular fever • Hepatitis • Malaria s
69. Malignancy • Metastatic or primary • Myeloma • Leukemia • Lymphoma
70.misc • Sickle cell anaemia • Hemolytic anaemia • porphyria
.Ascities and portal hypertension • 71.Cirrhosis • 72.Portal nodes • 73.Budd-chiari syndrome • 74.IVC or portal vein thrombosis
qumber: defination DM • Lack of or diminished effectiveness of endogenous insulin and characterized by hypoglycemia • Two types
Glucose normal • Normal glucose range • 3.5 to 5.5 mmol/lit • Ketone breath • Ketoacidosis • Secoondary DM • developing After some disease,drugs or pancreatic surgery
WHO criteria for labelling glucose • Fasting plasma venous glucose level • Equal to or >7mmol/lit • OGTT>? To label DM • 11.1mmol?lit
HBA1c specifity n sensitivity • 99.6% n 99% • Urine glycoseuria specificity and sensitivity • 33% n 90%
Which diuretic u will use in renal impairment in DM • ACE inhibitors • What care to be taken in thyazolidine • LFTs monthly bc hepatotoxity
Thiazolidines and biguanides MOA? • Increase recetpor sensitivity • Alpha glycosidase inhibitors MOA • Stop starch conversion into glucose • Stop hepatic gluconeogenesis
Side effects of Alpha glucosidase inhibitors • Flatus abdominal distension
Cause of hypoglycemia in diabetics • Insulin and oral hyperglycemic
CAUSES • Cause of hypoglycemia in non diabetic • EXPLAIN • Exogenous drugs • Insulin • Oral hypoglycemics • Alcohol • Others quinine sulphate,pentamidine,quinolones
( EXPLAIN ) • Pitu insufficiency • Liver failure’ • Addison’s disease • Islet cell tumor /insulinoma • Immune hypoglycemia • Nonpancreatic neoplasia
PRESENTATIONS • HI or norm insulin + no ketones • = insulinoma , sulphonylurea, insulin auto anti bodies • Low or undetectable insulin + no ketones • = non pancreatic neoplasia and ins rec antibodies • Ins low or undetected + hi ketones • =adrenal or pitutary failure
Confirm test for insulinomas • Suppresive test = insulin iv inf and measure c – peptide
Investigations • BSR by lab or glucometer • Exclude liver failure or malaria • LFT and Mp slide • OGTT for post prandial hypoglycemia • 72 hr fast and BSR monitoring for fasting hypoglycemia
TREATMENT • oral sugar 25-50g iv glucose stat as 25% D/W • Glucagon 0.5 – 1.5mg iv • Frequent CHO meals • Long acting starch for recurrence • Guar and pectin instead of CHO incase of recurrence after starch
qumber: pediatrics limp • 5.painful arthritis+macular rash+fever+lymphadenopathy • Juvenile ideopathic arthritis • 6.6yr+painless Ar+flattened epiphyseal ends • Perthes disease • 7.3 yr+painless limp+skin crease • Congenital dislocation of hip
qumber: pediatrics Motor abnormalitis and drug • 5.spastic diplegia • Cerebral palsy • 6.Ataxia • Postvaricella infection • Mefloquine side effects • neuropsychiatric
qumber: pediatrics Biopsy • 5.werdnig-Hoffman disease or spinal muscular atrophy • Muscle biopsy • 6.secondary sclerosing panencephalitis • Brain bipsy • Celiac disease • Villus atrophy on jejunal biopsy • Hirschsprungs disease • Rectal biopsy
qumber: pediatrics stridor • 5.usually well but worse during night • ALTB • Prevention of recurrent moderate asthma • Pulmicort inhaler • Treatment of mild asthma • Bricanyl inhaler asthma
qumber: pediatrics • 5.newborn+lymphedema of feet+low hairline+small chin • 45XO, turner • 6.15 gynocomestia +poorly developed testes • Klinefelter, 46XXXy • Small chin,mental retardation+abnormally shaped souls • Trisomy 18s • Cleft palatte aortic arch+Abnormal T function • Deletion of 22q11 Digeorge syndrome • Hypotonicnewborn brachycephaly and duodenal atresi • Trisomy, down syndromea
qumber: pediatrics epilepsy • .10 yr+twitching corner of his mouth,arm leg consious • Benighn rolandic epilepsy • Sixmonth+shortlived flexion neck&limbs • Infantile spasms
qumber: pediatrics • 8.Pallor of palmer crease • Anemia • 9.Palmer erythema • Cirrhosis pregnancy polycythemia • 10.Pigmentation of creases • Normal in Asian/blacks Addison
qumber: pediatrics Viral infections of childhood • Rash+cervical lymphadenopathy+arthritis • rubella • Rash Lymphadenopathy organomegaly • EBV • Hand foot mouth disease • Coxsackie A • Diarrhea URTI conjunctivitis • Adenovirus • Roseola infantum • HHV
qumber: Bed side Marking= wrong ones • 9/24/04 30/38 =78%