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An Introduction to Systematic Reviews

An Introduction to Systematic Reviews. Shakila Thangaratinam Professor of Maternal and Perinatal Health Women’s Health Research Unit R & D Director of Women’s Health Barts Health NHS Trust. Systematic review. What is it?. Traditional reviews. Search and acquisition of evidence not clear

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An Introduction to Systematic Reviews

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  1. An Introduction to Systematic Reviews ShakilaThangaratinam Professor of Maternal and Perinatal Health Women’s Health Research Unit R & D Director of Women’s Health Barts Health NHS Trust

  2. Systematic review • What is it?

  3. Traditional reviews Search and acquisition of evidence not clear Personal interests of the authors Reliability issues

  4. What is a systematic review? Systematic undertaking of a review with a focused research question that tries to identify, appraise, select and synthesise all high quality research evidence relevant to that question. 

  5. Systematic reviews • What is it? • Why do we need it?

  6. Why do we need Systematic reviews • New evidence changes patient management • Delay in implementation can harm patient. • It is difficult to get evidence when it is needed • Knowledge and clinical performance deteriorates with time without an attempt to keep up-to-date • Traditional continuing education programs do not improve clinical performance • EBM keeps its practitioners up-to date

  7. Why do systematic reviews? Support Evidence Based Practice Research Inform clinical policy Publication Personal professional development

  8. Systematic reviews • Review of reviews Survey of practice Yes No Primary studies Good quality reviews Poor quality reviews Yes No Conduct Systematic reviews Good quality study Poor quality study EBM Design and conduct primary study

  9. Systematic reviews • What is it? • Why do we need it? • How to do them?

  10. How to do systematic reviews? Formulate clear clinical questions from our knowledge needs • Search the literature to identify relevant articles • Critically appraise the evidence for its validity and usefulness • Synthesise evidence

  11. Workshop Objectives • Aim: Familiarisation with Systematic reviews • Objectives: • Literature Retrieval • Critical Appraisal of: • Therapy and Diagnosis • Primary studies and Systematic Reviews • Use of clinically meaningful statistics

  12. Search bibliographic databases Design search strategy Formulate research question The systematic review process Further selection of primary studies using inclusion criteria Identify possible papers from titles/abstracts Retrieve papers Formulate research / policy conclusions Quality appraisal Synthesis Extract data

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