Webinar on Graduate Project for Biopharma Students

1. Webinar on Graduate Projectfor Biopharma Students whether you are just starting out in the program, or already writing your paper, this webinar is for you! please attend: march 5th 7pm http://tinyurl.com/shrpbphe6200-p http://tinyurl.com/shrpbphe6200m session will be recorded

2. Preparing a Graduate Project in the UMDNJ MS CTS Program James L Parmentier, PhD. Associate Professor Biopharma Educational Initiative

3. IDST6980 - Aspects to Consider • Administrative • Research Design • Literature Research • Technical Writing • Oral Presentation • Administrative

4. Grad Project/Fieldwork Initiation Form Go to the Biopharma website > then to General Information > http://shrp.umdnj.edu/dept/biopharma/documents/GraduateProjectFieldworkInitiationForm.pdf Fill out the Graduate Project Fieldwork Initiation Form > Think about what you can do and/or want to do: Type of Experience? Contacts? Ability to Travel? Availability? Fax or email it to your Advisor

6. IDST6980 - Aspects to Consider • Research Design • Literature Research • Technical Writing • Oral Presentation

7. IDST6980 - Aspects to Consider • Research Design • Literature Research • Technical Writing

8. Research Design –It’s all about asking a good question

9. Research Design – It’s all about asking a good question So, what makes a good research question?

10. The foundation of a good research question has always been some frustrated person saying…

11. The foundation of a good research question has always been some frustrated person saying… There has to be a better way to do this!”

12. “There has to be a better way to do this!”“this” is an action, a problem or a thing.

13. “There has to be a better way to do this!”“better way” is a comparison statement.

14. “There has to be a better way to do this!”“has” (bolded) means it is important

15. “There has to be a better way to do this!”

16. “There has to be a better way to do this!”

17. Research Design –It’s all about asking a good question • The question must be answerable. • 2) The question must be relevant. • 3) The question must be feasible.

18. NIH Clinical Research Questions • Diagnosis • Etiology • Therapy • Prognosis

19. Centre for Evidence-Based Medicine • Frequency • Diagnosis • Prognosis • Therapy • Benefits and Harms

20. Among perimenopausal women, what is the effect of using hormone replacement therapy with drug X (versus no treatment) to reduce the incidence of hot flashes? simple

21. Among perimenopausal women, what is the effect of using hormone replacement therapy with drug X (versus no treatment) to reduce the incidence of hot flashes? Among school age children, how effective are specialized school-based physical activity programs (compared to standard programs) in bringing about weight loss? complex simple

22. The process is to use PICO questions P: Patient or population? I: Intervention (or exposure or diagnostic test)? C: Comparison: What is the main alternative compared with the focus situation? O: Outcomes: What is measured, improved, affected or accomplished?

23. PIC0 What is the effectiveness among healthy peri-menopausal women in the USof using drug Xcompared to using no treatment for decreasing the incidence of hot flashes (as measured by patient self-report)?

24. PIC0 What is the effectiveness among healthy peri- menopausal women in the USof using drug Xcompared to using no treatment for decreasing the incidence of hot flashes (as measured by patient self-report)? Among US overweight children what is the effect of a multi-disciplinary weight loss intervention compared to single-mode interventions for bringing about improved weight status (as measured by BMI and percent body fat)?

25. List of Suggested Topics: See the IDST6980-6989-M-Sp12: Graduate Project website

26. Searching the LiteratureIt’s all about finding the right information

27. Literature Research –It’s all about finding the right information • The information must be relevant. • 2) The information must be reliable and accessible. • The information must be interpretable.

28. Focused Medical-Scientific Literature Searching • Aggregators: OVID-SP, Embase.com, EDSCO Host, Wiley • Databases: Medline, Embase • PubMed (NCBI) • Boolean & Command-line searching (with tags) • MEDLINE formatting and MeSH

29. Drug-Focused Literature Searching February 27, 2012 https://sas.elluminate.com/site/external/jwsdetect/playback.jnlp?psid=2012-02-27.1604.M.FB161CDD6B76A23DB29DDF09989F52.vcr&sid=2009003 Carol Mitchell, MD

30. PubMed – www.pubmed.gov

31. 1 Searching the UMDNJ Library 2 3 4

32. Linking from PubMed to UMDNJ Click here Read more here

33. Linking from PubMed to UMDNJ Create your NCBI Account (Play around with it a little while) • Click on Site Preferences • Click on Filters and Icons • Click on LinkOut • Clink on Libraries • Clink on UMDNJ

34. Linking from UMDNJ to PubMed This time, click on “Our Campus Libraries”

35. Linking to PubMed from UMDNJ In the bar next to PubMed type in the “Name [au] AND NAME [JOURNAL]” of what you want to find.

36. Now hit “Find it in UMDNJ” and you will be taken directly to the full article…

37. Bingo!

38. Time and Resources Matter For a 4-6 month project, one person working 10-20 hours per week might expect to cover 15 -20 articles. Plan on working through an iterative process of fine- tuning your question and your literature searches.

39. Technical Writing It's all about communication

40. Technical Writing It's all about communication

41. Technical Writing It's all about communication “Whoever writes to a stranger should observe three points…………

42. Technical Writing It's all about communication That what he proposes be practicable; His proposition should be made in explicit terms, so as to be easily understood; 3) What he desires should in itself be reasonable. Hereby he will give a favorable expression of his understanding and create a desire of further acquaintance. Now it happens that you, Sir, were negligent in ALL these points.”

43. Technical Writing –It's all about communication!

44. Technical Writing –It's all about communication! • Know your story. • 2) Know your audience. • Write so you won't • be misunderstood.

45. Macrostructure of a Research Article Discussion Specific finding to wider implications Introduction General field or Context Methods Data and Results

46. Macrostructure of a Research Article Discussion Specific finding to wider implications Introduction General field or Context IMRAD Methods Data and Results LB Sollaci and MG.Pereira, The introduction, methods, results, and discussion (IMRAD) structure: a fifty-year survey, J Med Libr Assoc. 2004 July; 92(3): 364–371. PMCID: PMC442179

47. A Brief History of Scientific Writing GD Lundberg, How to Write a Medical Paper to Get It Published in a Good Journal Medscape General Medicine > Departments > Webcast Video Editorials Scientific Journals Peer Review IMRAD Lock, S: A difficult balance: Editorial peer review in medicine, nuffieldtrust.org, 1985 LB Sollaci and MG.Pereira, The introduction, methods, results, and discussion (IMRAD) structure: a fifty-year survey, J Med Libr Assoc. 2004 July; 92(3): 364–371. PMCID: PMC442179

48. The First Journals http://rstb.royalsocietypublishing.org

49. The Author's Advantage

50. Writing an Introduction Move 1  - Establish a territory Move 2  - Establish a niche Move 3  - Occupy the niche