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APPROACH TO VOMITING IN CHILDREN. Maria Naval C. Rivas, M.D. Department of Pediatrics The Medical City. APPROACH TO VOMITING IN CHILDREN. VOMITING
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APPROACH TO VOMITING IN CHILDREN Maria Naval C. Rivas, M.D. Department of Pediatrics The Medical City
APPROACH TO VOMITING IN CHILDREN VOMITING - forceful oral expulsion of gastric contents associated with contraction of the abdominal and chest wall musculature. This process is coordinated in the medullary vomiting center. NAUSEA - sensation of impending emesis and is frequently accompanied by autonomic changes, such as increased heart rate and salivation
PATHOPHYSIOLOGY afferent neural pathways from digestive organs afferent neural pathways from non-digestive organs chemoreceptor trigger zone in the area postrema on the floor of 4th ventricle CNS centers (brainstem and vestibular systems) activation of the emetic center of the medulla
ETIOLOGY • Infants / Neonates Acute viral gastroenteritis Gastroesophageal reflux disease Pyloric stenosis Intestinal obstruction (eg, meconium ileus, volvulus, intestinal atresia, stenosis) Intussusception (should be considered in an older infant ≥ 3 mo) Others: sepsis, food intolerance, metabolic disorders
ETIOLOGY • Older Children Acute viral gastroenteritis Serious infections: meningitis, acute pyelonephritis Acute abdomen Increased intracranial pressure 2’ space-occupying lesion Cyclic vomiting
CYCLIC VOMITING - syndrome with numerous episodes of vomiting interspersed with well intervals - onset: 3-5 years of age - duration of vomiting: 2-3 days - frequency: 4 or more episodes per hour - prodrome: nausea, lethargy, headache, fever - precipitants: stress and excitement - Idiopathic type: migraine variant - Tx: rectal antiemetics
ETIOLOGY • Adolescents Acute viral gastroenteritis Pregnancy Eating disorders: Bulimia Toxic ingestions
BULIMIA - defined in DSM-IV as: 1. recurrent episodes of binge eating 2. during the binges, a fear of not being able to stop eating 3. regularly engaging in self-induced vomiting, use of laxatives, rigorous dieting to counteract the effects of binge eating 4. minimum of 2 binge eatings per week for 3 mos. 5. self-evaluation is unduly influenced by body weight and shape - Tx: psychotherapy, behavior modification, nutritional rehabilitation, anti-depressants
Toxic Ingestion Cholinergic Syndromes confusion GI cramping CNS depression vomiting weakness diaphoresis salivation muscle fasciculations lacrimation miosis urinary/fecal incontinence Causes: organophosphate & carbamate insecticides physostigmine, edrophonium, mushrooms
EVALUATION OF A CHILD WITH VOMITING • Assessment of severity Presence of dehydration Surgical Life-threatening disorder • Identification of cause
EVALUATION OF A CHILD WITH VOMITING History of Present Illness onset frequency character ( projectile, bilious, amount) pattern of vomiting ( after feeding? only with certain type of food? in the mornings? recurrent, cyclic episodes?) assoc s/sx (diarrhea, fever, abdominal pain)
Review of Systems Metabolic disorder: failure to thrive, poor suck, weakness Intestinal obtsruction: delay in passage of meconium, abdominal distention, lethargy Intracranial disorder: headache, nuchal rigidity, vision change
Review of Systems Eating disorder: food bingeing or signs of distorted body image Pregnancy: missed periods and breast swelling Rash: eczematous: food intolerance petechial: infection, CNS infection urticarial: food allergy Meningitis, Pyelonephritis or Appendicitis: fever with headache, back pain, or abdominal pain
Past Medical History Acute Gastroenteritis: history of travel Intracranial Pathology: recent head trauma Pregnancy: unprotected intercourse
DIAGNOSTIC APPROACH TO A CHILD WITH VOMITING Clinical Fecalysis Stool culture Empiric trial of acid suppression Esophageal & Upper GI contrast study
Ultrasonography of pylorus Upper GI contrast study Abdominal x-ray Upper GI study or contrast enema
Abdominal ultrasonography Rectal manometry Rectal biopsy Abdominal UTZ Contrast studies
CBC blood, urine, CSF cultures Chest x-ray if pulmonary symptoms Elimination diet
Ultrasonography Brain CT without contrast
Consequences of vomiting 1. Metabolic: potassium deficiency alkalosis sodium depletion 2. Nutritional 3. Mechanical injuries to esophagus and stomach - Mallory Weiss, Boerhaave’s syndrome 4. Dental erosions and caries 5. Purpura
Management 1. management of complications - fluid and electrolytes - nutrition - decompression 2. management of etiology - non-pharmaceutical - pharmaceutical - surgical