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Time Since Randomization

Aldo-DHF Randomized Controlled Trial Improved diastolic function after 1 year of spironolactone does not improve exercise capacity. Peak V• O 2. E/e ´ medial velocity ratio. Placebo. Spironolactone. P <.001. P <.001. P = .81. Change in Peak VO 2 , mL /min/kg. Change in E/e´.

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Time Since Randomization

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  1. Aldo-DHFRandomizedControlledTrialImproved diastolic function after 1 year of spironolactone does not improve exercise capacity Peak V• O2 E/e´ medialvelocity ratio Placebo Spironolactone P <.001 P <.001 P = .81 Change in Peak VO2, mL/min/kg Change in E/e´ P = .57 Time SinceRandomization Edelmann et al., 2013 JAMA 309(8):781-791

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