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TB MAC (Tuberculosis Modelling and Analysis Consortium) exists to address the complex natural history of TB and quantify uncertainty in order to compare strategies and range of interventions. Modelers, economists, and decision makers collaborate to provide data-informed guidance, despite limited data, models, and coordination. TB MAC targets, guidance, benchmarks, and reporting templates help improve TB policy and practice globally.
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Why does TB MAC exist? Complex Natural History Range of settings Compare strategies, quantify uncertainty Range of interventions
Why does TB MAC exist? Modelers & economists Decision makers Limited data, models and modellers Data & Country Stakeholders Decision-makers & modellers need data-informed guidance Lack of co-ordination
Who are TB MAC? Katherine Floyd WHO • Anna Vassall • LSHTM • Anna Bershteyn • IDM • Hsien-Ho Lin • National Taiwan University • Geoff Garnett BMGF • David Dowdy JHU • Nick Menzies Harvard • Ted Cohen Yale • Michael KimerlingKNCV Steering Committee Jeremiah C. Muhwa The Union Liz Corbett LSHTM Philippe Glaziou WHO Geoff Garnett BMGF SahuSuvanand StopTB Adam Macneil CDC Johannes Hunger GFATM David Wilson World Bank SevimAhmedovUSAID Carol Levin UW Knut Lönnroth KI Advisory Panel Finn McQuaid • Kristian Godfrey Richard White Madeleine Clarkson Secretariat (LSHTM)
What does TB MAC do? At a global & country level StrengtheningNetworks START 1. • Decision makers • Modellers • Economists Improved TB Policy & Practice & Creating solutions 2. Increased Efficacy Effectiveness • Resources 3. Empowering decision makers • Equipped
TB MAC activities: a closer look 1. Targets 2. Guidance 3. Benchmarks 2012 2013 2014 2015 2016 2017 2018
TB MAC Targets Multi-modelling group exercise 2025 WHO global TB Targets China, India, South Africa
TB MAC Targets Targets Targets multiple interventions multiple interventions multiple interventions single intervention single intervention single intervention
TB MAC Targets Percent reduction in TB incidence (2015-2025) with aggressive action on TB CHINA INDIA SOUTH AFRICA • Different models • Samecountries • Same policies • Same measures • Different results Percent reduction (%)
TB MAC Targets • Different models • Samecountries • Same policies • Same measures • Different results Incremental Costs (US$, mil.) DALYs Averted (mil.)
TB MAC Guidance Modelers & economists Funders & technical experts Country Stakeholders
Identified need Benchmarks Targets Guidance Put into practice
TB MAC Benchmarks Benchmarks Reporting template Review process
Influenced development of country level models & methods Influenced development of global level models & methods Provided evidence at high-level meetings Contributed to recommendations TB MAC impact Supported WHO Task Force Helped foster links
Thank You www.tb-mac.org @tb_mac