Inorganic & Organometallic Research Projects/Directions in the Peters Lab

Inorganic & Organometallic Research Projects/Directions in the Peters Lab Greg Peters Elmira College 10 February 2011

On Today’s Menu • Background info…a bit about me • Group/Directional approach • Projects 1-3 • Future Directions

Inorganic “Playground”

Organic Periodic Table C H N O F B metals Li Si P S Cl Na Mg Br K I metals

Three Distinct Directions/Projects • Suitable for students right out of CHE 1511 (or 1925). Inspire you to take CHE 3030? • Works with existing Departmental Instrumentation • NMR, IR, GC-MS, some UV-Vis • appeals to multiple student goals • Project nearing completion(quicker publication) • Coordination Chemistry projects (embryonic) • di-phosphane ligands (completely yours!) • RESULTS!! Publication in 2009, two in 2011 (!!), one in prep.

Direction 2 • Direction 3 Preparation of Platinum Group Metal Complexes Ligand Synthesis and Coordination Chemistry diphosphane style!! Electron rich Electron poor Direction 1 Ligand Synthesis and Coordination Chemistry

Survey of Typical OM Ligands P(tBu)3 P(CxF2x+1)3 PPh3 olefins P(OPh)3 PF3 Size PMe3 P(OMe)3 CO Electron Acceptor Ability - few ligands bridge the electronic gap - massive voids were recently noted [Cundari, JACS, 2003, 4318]

Phosphane Ligands • Commonly utilized inorganic ligand • Key Properties (all readily controlled) • sterics • sigma donation (electronics)

Phosphine Manipulation • Sterics—Simple as changing the hydrocarbon ligand (Me, Et, tBu, Ph, etc) • s-donor / p-acceptor character not as simple

Our Approach—bridge the gap • Prepare phosphine ligands with an electronic influence of P(OR)3 • Modification of PR3 framework with Rf • Similar to F/H swap • Chose Rf = C2F5, sought R2PRf series • R = Me, Et, iPr, tBu, Ph

Project 1—Generic Ligand Synthesis Affectionately called pfepp (pentaflouroethyl)diphenylphosphine pfepp has an awful lot of cousins/relatives; he has a huge family!! For students out there…you can help add to the family!!

Ligand Preparation Note stability difference of lithium reagent HFC procedure developed Affectionately called pfepp (pentaflouroethyl)diphenylphosphine

You make it first…you name it!! Michelle Choate Jennifer Phelps Published in JOMC 2011 Project in progress When do you want it Published?

‘flip’ Data…born 3 February 2011 31P NMR spectrum, oodles of fluorine coupling

Ligand Coordination Chemistry Straightforward reaction, alkane solvent Establish electronic influence of ligand

pepy molly—sounds like a cheerleader…doesn’t it?…but we did discuss three Projects…yes?

Project 2—Molly Has Friends!! Choate et al. ActaCryst. E 2011

Remember that Playground?? Think about this…so many ligands…never before synthesized. SO MANY METALS!! SO MANY OPPORTUNITIES

…And that 3rd Project? Electron rich Electron poor This one really excites me…cutting edge stuff Take lab knowledge and extend it. I referred to it as inductively ‘unusual’

Synthetic ‘work of fiction’? Nah! Two different types in fact!!

Future Directions?? Just Imagine Work WITH me…I need YOUR help…where do you fit into this scheme? Imagine that! You WILL get published You WILL make things NO ONE else has ever made! So many projects…

Acknowledgements --Mentoring Committee, Wilkes University --National Science Foundation -- Michelle Choate -- Jennifer Phelps -- Jaimee Ash -- Justin Spott -- Sara Frawley -- Dr. Russ Baughman -- Jennifer Seat -- Dr. Jason Palcic -- Misha Golynskiy -- Karl Pittard -- Mary Ross -- Johnny Giles

Inorganic & Organometallic Research Projects/Directions in the Peters Lab