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Emphysematous abomasitis in one month old lambs. Hein Snyman BVSc DVSc Anatomic Pathology Resident Department of Pathobiology Ontario Veterinary College University of Guelph. Signalment. One month old lambs (n=3) Male Rideau Arcott. History. Novice small scale operation
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Emphysematous abomasitis in one month old lambs Hein Snyman BVSc DVSc Anatomic Pathology Resident Department of Pathobiology Ontario Veterinary College University of Guelph
Signalment • One month old lambs (n=3) • Male • Rideau Arcott
History • Novice small scale operation • Farmer away on the weekend • Returned to find 3 lambs dead • Acute death within last 36 hours • Growing well
Gross findings • Good body condition • Fibrinous peritonitis & serosal petechiae • Abomasal mucosal haemorrhage, necrosis and ulceration • Exuberant autolysis of the kidney and liver
Ancillary diagnostics • Faecal flotation – NAD • Bacterial culture: 4 + Clostridium perfringens 3 + Mannheimiahaemolytica • Clostridial Fluorescent antibody test (FAT) Clostridium septicum www.vet.uga.edu
Diagnosis Mdx- Emphysematous, necrotizing and suppurative abomasitis, trans mural, regionally extensive, acute. Edx- Clostridial gangrenous abomasitis/Braxy Etiology – Clostridium septicum & C. perfringens
Braxy • Highly fatal • Acute to peracute • Treatment rarely successful • NW Europe • Norway, Denmark, North Germany, Iceland and the Faroe islands – Bradsot • UK, Ireland, North America and Australia
Braxy • Low prevalence • Cold winters • Overwintering on summer pasture • Autumn, early to mid winter • North America – early spring
Braxy • Severe oedema, necrosis and gangrenous inflammation of the mucosa of the abomasum • C. septicum, C. novyi, C. perfringenstype A & C
Braxy • Good condition • 6 to 18 months • Morbidity up to 50 % • Calves • Abomasal ulcers
Pathogenesis • Poorly understood • Mucosal invasion and proliferation without any predisposing lesion • Coarse and frozen vegetation • Toxin production • Abomasalcanula – Glucose & VFA’s • Centrifugal emphysematous lesions Ellis T.M., Rowe J.B. and Lloyd J.M. (1983). Acute abomasitis due to Clostridium septicuminfection in experimental sheep. Aust. Vet. J. 60, 308-309.
Prevention • Immunoprophylaxis • Toxoid/Bacterin • No vaccination protocol • No Clostridial vaccines
References • Coetzer J.A.W., Tustin R.C. Infectious diseases of livestock, 2nd Edition, Volume Three, Section Five: Bacterial diseases, 183 Clostidiumsepticuminfections, pg. 1869-1873. • Ellis T.M., Rowe J.B. and Lloyd J.M. (1983). Acute abomasitis due to Clostridium septicuminfection in experimental sheep. Aust. Vet. J. 60, 308-309. • Eustis S.L. and Bergeland M.E. (1981). Suppurative abomasitis associated with Clostridium septicuminfection. J. Am. Vet. Med. Assoc. 178, 732-734. • Songer JG. (1996). Clostridial enteric diseases of domestic animals. Clin. Microbiol. Rev. 9, 216-234.