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第四章 影响药物效应的因素及合理用药

第四章 影响药物效应的因素及合理用药. 机体方面的因素 : 年龄 性别 精神因素 : 安慰剂 (placebo) 病理状态 遗传因素 昼夜节律. 药物方面的因素 : 药物相互作用 协同 (synergism), 拮抗 (antagonism) 长期连续用药 习惯性 (habituation) --- 精神上的依赖 成瘾性 (addiction) --- 躯体性依赖，一旦 停药会产生戒断现象 (abstinence syndrome) 。. 耐受性 (Tolerance): 连续用药后产

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第四章 影响药物效应的因素及合理用药

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  1. 第四章 影响药物效应的因素及合理用药 • 机体方面的因素: • 年龄 • 性别 • 精神因素: 安慰剂(placebo) • 病理状态 • 遗传因素 • 昼夜节律

  2. 药物方面的因素: • 药物相互作用 协同(synergism), 拮抗(antagonism) • 长期连续用药 习惯性(habituation) ---精神上的依赖 成瘾性(addiction) --- 躯体性依赖，一旦 停药会产生戒断现象 (abstinence syndrome)。

  3. 耐受性(Tolerance):连续用药后产 生的药物反应性降低。 快速耐受性(Tachyphylaxis), 耐药性(Resistance) 增敏性及撤药症状

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