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Exercise metabolism – wrap up

Exercise metabolism – wrap up. Validity of VO 2 as measure of exercise metabolism EPOC – caused by lactate clearance?. Exercise metabolism – wrap up. Validity of VO 2 as measure of exercise metabolism Assumptions : 1. All ATP resynthesis must be from respiration

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Exercise metabolism – wrap up

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  1. Exercise metabolism – wrap up • Validity of VO2 as measure of exercise metabolism • EPOC – caused by lactate clearance?

  2. Exercise metabolism – wrap up • Validity of VO2 as measure of exercise metabolism • Assumptions: • 1. All ATP resynthesis must be from respiration • 2. ATP and CP stores are maintained • 3. Protein metabolism is nonexistent

  3. Exercise metabolism Validity of VO2 as measure of exercise metabolism Assumptions: 1. All ATP resynthesis must be from respiration Measurement must be made during steady-state submaximal exercise Brooks et al.

  4. OXYGEN DEFICIT Powers and Howley, Exercise Physiology, 2004

  5. Exercise metabolism All ATP resynthesis must be from respiration Brooks et al.

  6. Exercise metabolism Blood lactate during exercise Seeherman et al., Resp Physiol 44: 11, 1981

  7. O2 Uptake vs Time and Power Output Wilmore and Costill, Physiology of Sport and Exercise,Human Kinetics, 2004

  8. Exercise metabolism [LA] mg% Error Leg LA release Leg net LA exchange Brooks et al.

  9. Exercise metabolism Brooks et al.

  10. Exercise metabolism Brooks et al.

  11. OXYGEN DEFICIT AND EPOC (excess post-exercise oxygen consumption) Wilmore and Costill, Physiology of Sport and Exercise,Human Kinetics, 2004

  12. OXYGEN DEFICIT AND EPOC (excess post-exercise oxygen consumption) Is the EPOC caused by need to clear lactate?

  13. Exercise metabolism “alactacid” debt (fast component) “lactacid” debt (slow component) Brooks et al.

  14. Exercise metabolism However, the Margaria et al. conclusions resulted from using a relatively high intensity exercise Brooks et al.

  15. Exercise metabolism Metabolic fate of lactate after exercise

  16. Exercise metabolism Brooks et al.

  17. Exercise metabolism Brooks et al.

  18. Exercise metabolismWhat then is the explanation for the EPOC? 1. Hyperthermia a. Q10 effect b. Some uncoupling(?) 2. FFA causing uncoupling (?) 3. Catecholamines and thyroid hormone increasing Na+-K+ pump activity 4. Elevated mitochondrial Ca2+ pumping 5. Elevated catecholamine stimulation of metabolism

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