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肠胃道易激综合症 (IBS) 对食物的过敏 及 饮食控制. 黄光明医生 副顾问 国大医院. Gut Bacteria and the Irritable Bowel Syndrome. What is Irritable Bowel Syndrome?. Abdominal pain Bloating Constipation Diarrhoea Eructation Flatulence ‘Gastric’. The Role of Microbes in IBS. Post-infectious IBS
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肠胃道易激综合症(IBS)对食物的过敏及饮食控制肠胃道易激综合症(IBS)对食物的过敏及饮食控制 黄光明医生 副顾问 国大医院
What is Irritable Bowel Syndrome? • Abdominal pain • Bloating • Constipation • Diarrhoea • Eructation • Flatulence • ‘Gastric’
The Role of Microbes in IBS • Post-infectious IBS • Small intestinal bacterial overgrowth • Effect of antibiotics on IBS symptoms • Probiotic treatment for IBS
Salmonella Campylobacter Shigella IBS can develop after Infection The risk is as high as 12x more than people without infection
Antibiotics, good or bad? • Antibiotic treatment may improve IBS symptoms if bacterial overgrowth is present • But, IBS may also develop in some patients after receiving antibiotics for other infections
What are probiotics? • Greek: ‘for life’ • Live organisms that, when ingested in adequate amounts, exert a health benefit on the host • Eg Lactobacilli, Bifidobacteria, Saccharomyces boulardii
Effect of probiotics on the intestine • Reduce amount of harmful bacteria • Control inflammation • Alter the intestinal movements • Reduce gas production
Probiotics (others) in IBS Bifidobacterium infantis VSL#3 = Streptococcus thermophilus, Lactobacillus spp, Bifidobacteria spp
Conclusions • IBS is a common condition that can severely affect a person’s quality of life. • Probiotic organisms may be useful in the treatment of IBS. • However, the benefits in IBS are brought about by some but not all probiotic organisms. • Different probiotic organisms have different effects; Some may have opposite effects on the intestines.